1CVS

CRYSTAL STRUCTURE OF A DIMERIC FGF2-FGFR1 COMPLEX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	FIBROBLAST GROWTH FACTOR 2	polymer	132	15110.3	2	UniProt (P09038) Pfam (PF00167) In PDB	Homo sapiens (human)
2	C, D	FIBROBLAST GROWTH FACTOR RECEPTOR 1	polymer	225	25274.8	2	UniProt (P11362) Pfam (PF07679) In PDB	Homo sapiens (human)
3	A, B	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)

Sequence modifications

A, B: 15 - 146 (UniProt: P09038)

PDB	External Database	Details
Ser 69	Cys 79	engineered mutation
Ser 87	Cys 97	engineered mutation

C, D: 141 - 365 (UniProt: P11362)

PDB	External Database	Details
Gln 185	Asn 175	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	80770.3
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	81154.5

*Water molecules are not included.