1CVS
CRYSTAL STRUCTURE OF A DIMERIC FGF2-FGFR1 COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | FIBROBLAST GROWTH FACTOR 2 | polymer | 132 | 15110.3 | 2 | UniProt (P09038) Pfam (PF00167) | Homo sapiens (human) | |
| 2 | C, D (C, D) | FIBROBLAST GROWTH FACTOR RECEPTOR 1 | polymer | 225 | 25274.8 | 2 | UniProt (P11362) Pfam (PF07679) | Homo sapiens (human) | |
| 3 | E, F, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) |
Sequence modifications
A, B: 15 - 146 (UniProt: P09038)
C, D: 141 - 365 (UniProt: P11362)
| PDB | External Database | Details |
|---|---|---|
| Ser 69 | Cys 79 | engineered mutation |
| Ser 87 | Cys 97 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gln 185 | Asn 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 80770.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 81154.5 |
