1CSB

Crystal structure of cathepsin b inhibited with CA030 at 2.1 angstroms resolution: A basis for the design of specific epoxysuccinyl inhibitors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, D)	CATHEPSIN B light chain	polymer	47	5213.8	2	UniProt (P07858)	Homo sapiens (human)
2	B, D (B, E)	CATHEPSIN B heavy chain	polymer	205	22437.9	2	UniProt (P07858) Pfam (PF00112)	Homo sapiens (human)
3	E, F (A, E)	N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-isoleucyl-L-proline	non-polymer		372.4	2	BIRD (PRD_000310) Chemie (EP0)
4	G, H, I, J (A, B, D, E)	water	water		18.0	542	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55303.5
Non-Polymers*	Number of molecules	2
	Total formula weight	744.8
All*	Total formula weight	56048.3

*Water molecules are not included.