1CPI
REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES. DESIGN OF HYDROLYTICALLY STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10764.6 | 2 | UniProt (P03369) Pfam (PF00077) | HIV-1 PR | |
| 2 | C (C) | CYCLIC PEPTIDE INHIBITOR | polymer | 6 | 767.7 | 1 | BIRD (PRD_000407) | ||
| 3 | D, E, F (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | G, H, I (A, B, C) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
| PDB | External Database | Details |
|---|---|---|
| Aba 67 | Cys 123 | conflict |
| Aba 95 | Cys 151 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 22297.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 22585.2 |
