1C5R
STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1-BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (TRYPSIN) | polymer | 223 | 23324.3 | 1 | UniProt (P00760) Pfam (PF00089) | Bos taurus (cattle) | |
| 2 | B (A) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F (A) | 4-IODOBENZO[B]THIOPHENE-2-CARBOXAMIDINE | non-polymer | 303.1 | 1 | Chemie (ESI) | |||
| 6 | G (A) | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23324.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 724.4 | |
| All* | Total formula weight | 24048.7 |
