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1C1W

RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
Thrombin light chainpolymer364096.51UniProt (P00734)
Pfam (PF09396)
Homo sapiens (human)
2B
(H)
Thrombin heavy chainpolymer25929780.21UniProt (P00734)
Pfam (PF00089)
Homo sapiens (human)
3C
(I)
Hirudin-2polymer111491.51UniProt (P28504)Hirudo medicinalis
4D, E, F
(L, H)
ZINC IONnon-polymer65.43Chemie (ZN)
5G
(H)
SODIUM IONnon-polymer23.01Chemie (NA)
6H
(H)
BIS(5-AMIDINO-2-BENZIMIDAZOLYL)METHANE KETONE HYDRATEnon-polymer366.41Chemie (BAH)
7I, J, K
(L, H, I)
waterwater18.0239Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight35368.3
Non-Polymers*Number of molecules5
Total formula weight585.6
All*Total formula weight35953.9
*Water molecules are not included.

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PDB entries from 2025-07-02

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