1C1B
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GCA-186
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HIV-1 REVERSE TRANSCRIPTASE (A-CHAIN) | polymer | 560 | 64594.9 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus 1 | |
| 2 | B (B) | HIV-1 REVERSE TRANSCRIPTASE (B-CHAIN) | polymer | 440 | 51357.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus 1 | |
| 3 | C (A) | 6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPYLURACIL | non-polymer | 330.4 | 1 | Chemie (GCA) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
B: 1 - 440 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Csd 280 | Cys 435 | modified residue |
| PDB | External Database | Details |
|---|---|---|
| Lys 172 | Arg 327 | conflict |
| Asn 428 | Gln 583 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115952.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 330.4 | |
| All* | Total formula weight | 116282.4 |
