1C0G
CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 228: Q228K/T229A/A230Y/E360H)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (S) | PROTEIN (GELSOLIN SEGMENT 1) | polymer | 127 | 14205.0 | 1 | UniProt (P06396) Pfam (PF00626) | Homo sapiens (human) | |
| 2 | B (A) | PROTEIN (CHIMERIC ACTIN) | polymer | 375 | 41732.6 | 1 | UniProt (P07830) Pfam (PF00022) | Dictyostelium discoideum Tetrahymena thermophila ( ) | |
| 3 | C, D, E (S, A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | F (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 5 | G, H (S, A) | water | water | 18.0 | 469 | Chemie (HOH) |
Sequence modifications
S: 4 - 127 (UniProt: P06396)
A: 1 - 375 (UniProt: P07830)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | cloning artifact |
| Gly 2 | - | cloning artifact |
| Ser 3 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Hic 73 | His 74 | modified residue |
| Ala 225 | Gln 226 | conflict |
| Lys 228 | Ala 229 | SEE REMARK 999 |
| Ala 229 | Thr 230 | SEE REMARK 999 |
| Tyr 230 | Ala 231 | SEE REMARK 999 |
| His 360 | Glu 361 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55937.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 627.4 | |
| All* | Total formula weight | 56565.0 |
