1BT5
CRYSTAL STRUCTURE OF THE IMIPENEM INHIBITED TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (BETA-LACTAMASE) | polymer | 263 | 28984.1 | 1 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) | Escherichia coli | |
| 2 | B, C, D, E, F... (A) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | J (A) | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid | non-polymer | 301.4 | 1 | Chemie (IM2) | |||
| 4 | K (A) | water | water | 18.0 | 347 | Chemie (HOH) |
Sequence modifications
A: 26 - 290 (UniProt: P62593)
| PDB | External Database | Details |
|---|---|---|
| Ile 84 | Val 82 | engineered mutation |
| Val 184 | Ala 182 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28984.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1069.9 | |
| All* | Total formula weight | 30053.9 |
