1BQN
TYR 188 LEU HIV-1 RT/HBY 097
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | REVERSE TRANSCRIPTASE | polymer | 558 | 64222.7 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus 1 | HIV-1 RT |
| 2 | B (B) | REVERSE TRANSCRIPTASE | polymer | 430 | 50175.7 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus 1 | HIV-1 RT |
| 3 | C (A) | (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE | non-polymer | 340.5 | 1 | Chemie (HBY) |
Sequence modifications
A: 1 - 558 (UniProt: P03366)
B: 1 - 430 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Leu 188 | Tyr 355 | engineered mutation |
| Gln 248 | Glu 415 | conflict |
| Ser 280 | Cys 447 | engineered mutation |
| Gln 546 | Glu 713 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Leu 188 | Tyr 355 | engineered mutation |
| Glu 242 | Gln 409 | conflict |
| Ala 278 | Gln 445 | conflict |
| Ser 280 | Cys 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114398.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 340.5 | |
| All* | Total formula weight | 114738.8 |
