1BL4
FKBP MUTANT F36V COMPLEXED WITH REMODELED SYNTHETIC LIGAND
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | PROTEIN (FK506 BINDING PROTEIN) | polymer | 107 | 11788.5 | 2 | UniProt (P62942) UniProt (P20071) Pfam (PF00254) | Homo sapiens (human) | FKBP |
2 | C, D (A, B) | {3-[3-(3,4-DIMETHOXY-PHENYL)-1-(1-{1-[2-(3,4,5-TRIMETHOXY-PHENYL)-BUTYRYL]-PIPERIDIN-2YL}-VINYLOXY)-PROPYL]-PHENOXY}-ACETIC ACID | non-polymer | 693.8 | 2 | Chemie (AP1) | |||
3 | E, F (A, B) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 107 (UniProt: P62942)
PDB | External Database | Details |
---|---|---|
Val 36 | Phe 36 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 23576.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1387.6 | |
All* | Total formula weight | 24964.5 |