1BIW
DESIGN AND SYNTHESIS OF CONFORMATIONALLY-CONSTRAINED MMP INHIBITORS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PROTEIN (STROMELYSIN-1 COMPLEX) | polymer | 173 | 19416.5 | 2 | UniProt (P08254) Pfam (PF00413) | Homo sapiens (human) | MMP3 |
| 2 | C, D, H, I (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, F, G, J, K... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | M (B) | N1-HYDROXY-2-(3-HYDROXY-PROPYL)-3-ISOBUTYL-N4-[1-(2-METHOXY-ETHYL)-2-OXO-AZEPAN-3-YL]-SUCCINAMIDE | non-polymer | 415.5 | 1 | Chemie (S80) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38833.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 917.6 | |
| All* | Total formula weight | 39750.7 |
