1B7X
STRUCTURE OF HUMAN ALPHA-THROMBIN Y225I MUTANT BOUND TO D-PHE-PRO-ARG-CHLOROMETHYLKETONE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (THROMBIN LIGHT CHAIN) | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (B) | PROTEIN (THROMBIN HEAVY CHAIN) | polymer | 259 | 29730.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (C) | PROTEIN (INHIBITOR) | polymer | 3 | 419.5 | 1 | Homo sapiens (human) | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
B: 16 - 247 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ile 225 | Tyr 600 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34246.2 | |
| All* | Total formula weight | 34246.2 |
