1AIX
HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROVAL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | ALPHA-THROMBIN (SMALL SUBUNIT) | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | ALPHA-THROMBIN (LARGE SUBUNIT) | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (I) | HIRUGEN | polymer | 12 | 1606.6 | 1 | UniProt (P28510) UniProt (by SIFTS) (P28507) | Hirudo medicinalis (medicinal leech) | |
| 4 | D (H) | PHENYLMETHYLENECARBOXY-(METHYLENEAMINO-FORMYL-DIPHENYLMETHYL)METHY-PRO-BOROVAL | non-polymer | 567.4 | 1 | Chemie (T19) | |||
| 5 | E, F, G (L, H, I) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
I: 53 - 64 (UniProt: P28510)
| PDB | External Database | Details |
|---|---|---|
| Glu 54 | Gly 61 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35483.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 567.4 | |
| All* | Total formula weight | 36050.8 |
