1AIO

CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA CONTAINING THE MAJOR ADDUCT OF THE ANTICANCER DRUG CISPLATIN

Replaces:  1GPG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	DNA (5'-D(*CP*CP*(BRU)P*CP*TP*[PT(NH3)2(GP*GP)]*TP*CP*TP*CP*C)-3')	polymer	12	3630.2	2
2	B, D (B, D)	DNA (5'-D(*GP*GP*AP*GP*AP*CP*CP*AP*GP*AP*GP*G)-3')	polymer	12	3761.5	2
3	E, F (A, C)	Cisplatin	non-polymer		300.0	2	Chemie (CPT)
4	G, H, I, J (A, B, C, D)	water	water		18.0	62	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	14783.3
Non-Polymers*	Number of molecules	2
	Total formula weight	600.1
All*	Total formula weight	15383.4

*Water molecules are not included.