1AFA
STRUCTURAL BASIS OF GALACTOSE RECOGNITION IN C-TYPE ANIMAL LECTINS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (1, 2, 3) | MANNOSE-BINDING PROTEIN-A | polymer | 154 | 17025.3 | 3 | UniProt (P19999) Pfam (PF00059) | Rattus norvegicus (Norway rat) | CL-QPDWG |
| 2 | D, I, M (1, 2, 3) | methyl beta-D-galactopyranoside | non-polymer | 194.2 | 3 | Chemie (MBG) | |||
| 3 | E, F, G, J, K... (1, 2, 3) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) | |||
| 4 | H, Q (1, 3) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | R, S, T (1, 2, 3) | water | water | 18.0 | 391 | Chemie (HOH) |
Sequence modifications
1, 2, 3: 73 - 226 (UniProt: P19999)
| PDB | External Database | Details |
|---|---|---|
| Gln 185 | Glu 202 | engineered mutation |
| Asp 187 | Asn 204 | engineered mutation |
| Trp 189 | His 206 | engineered mutation |
| Tyr 190 | Gly 207 | engineered mutation |
| Gly 191 | Ser 208 | engineered mutation |
| His 192 | - | insertion |
| Gly 193 | - | insertion |
| Leu 194 | - | insertion |
| Gly 195 | - | insertion |
| Gly 196 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 51075.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1014.2 | |
| All* | Total formula weight | 52090.0 |
