1AFA

STRUCTURAL BASIS OF GALACTOSE RECOGNITION IN C-TYPE ANIMAL LECTINS

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0001867	biological_process	complement activation, lectin pathway
1	0005537	molecular_function	mannose binding
2	0001867	biological_process	complement activation, lectin pathway
2	0005537	molecular_function	mannose binding
3	0001867	biological_process	complement activation, lectin pathway
3	0005537	molecular_function	mannose binding

Functional Information from PDB Data

site_id	11
Number of Residues	7
Details

Chain	Residue
1	ASP161
1	GLU165
1	ASP188
1	GLU198
1	ASP199
1	CA227
1	HOH262

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site_id	12
Number of Residues	6
Details

Chain	Residue
2	ASP161
2	GLU165
2	ASP188
2	GLU198
2	ASP199
2	CA1

---

site_id	13
Number of Residues	7
Details

Chain	Residue
3	ASP161
3	GLU165
3	ASP188
3	GLY193
3	LEU194
3	CA1
3	HOH260

---

site_id	21
Number of Residues	7
Details

Chain	Residue
1	GLU198
1	ASN210
1	ASP211
1	CA2
1	MBG1
1	GLN185
1	ASP187

---

site_id	22
Number of Residues	7
Details

Chain	Residue
2	GLN185
2	ASP187
2	GLU198
2	ASN210
2	ASP211
2	CA2
2	MBG3

---

site_id	23
Number of Residues	7
Details

Chain	Residue
3	GLN185
3	ASP187
3	GLU198
3	ASN210
3	ASP211
3	CA227
3	MBG2

---

site_id	31
Number of Residues	3
Details

Chain	Residue
1	GLU84
1	CA3
2	HOH245

---

site_id	32
Number of Residues	4
Details

Chain	Residue
2	GLU165
2	ASP199
2	HOH304
2	CA227

---

site_id	33
Number of Residues	5
Details

Chain	Residue
3	GLU84
3	CA3
3	HOH228
1	HOH251
3	HOH352

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Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	23
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVtivdngl.....WNDISCqasht.AVC

Chain	Residue	Details
1	CYS200-CYS222

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11850428","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1436090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7704532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9033386","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AFA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AFB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BCH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BCJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RTM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2MSB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KMB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11850428","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1436090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7704532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9033386","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RTM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2MSB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KMB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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