1AAX
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO BIS(PARA-PHOSPHOPHENYL)METHANE (BPPM) MOLECULES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN TYROSINE PHOSPHATASE 1B | polymer | 321 | 37277.5 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C, D (A) | 4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN | non-polymer | 360.2 | 2 | Chemie (BPM) | |||
| 4 | E (A) | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Ser 215 | Cys 215 | engineered mutation |
| Gly 304 | Glu 304 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37277.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 744.7 | |
| All* | Total formula weight | 38022.2 |
