1A81
CRYSTAL STRUCTURE OF THE TANDEM SH2 DOMAIN OF THE SYK KINASE BOUND TO A DUALLY TYROSINE-PHOSPHORYLATED ITAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... | SYK KINASE | polymer | 254 | 28831.9 | 6 | UniProt (P43405) Pfam (PF00017) In PDB | Homo sapiens (human) | |
| 2 | B, D, F, H, J... | T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN | polymer | 18 | 2284.3 | 6 | UniProt (P07766) Pfam (PF02189) In PDB | Homo sapiens | ITAM PEPTIDE |
Sequence modifications
B, D, F, H, J, L: 168 - 185 (UniProt: P07766)
| PDB | External Database | Details |
|---|---|---|
| Ptr 170 | Tyr 188 | CONFLICT |
| Ptr 181 | Tyr 199 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 186697.0 | |
| All* | Total formula weight | 186697.0 |
