1A31
HUMAN RECONSTITUTED DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*5IUP*5IU*TP*GP*AP*AP*AP*AP*AP*5IUP*5IUP*5IUP*5IUP*T)-3') | polymer | 22 | 7452.7 | 1 | |||
| 2 | B (D) | DNA (5'-D(*AP*AP*AP*AP*AP*TP*5IUP*5IUP*5IUP*5IUP*CP*AP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3') | polymer | 22 | 7161.9 | 1 | |||
| 3 | C (A) | PROTEIN (TOPOISOMERASE I) | polymer | 591 | 70118.8 | 1 | UniProt (TOP1_HUMAN) Pfam (PF02919) Pfam (PF01028) Pfam (PF14370) UniProt (by SIFTS) (P11387) | Homo sapiens (human) | |
| 4 | D, E, F (C, D, A) | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence modifications
A: 175 - 765 (UniProt: null)
| PDB | External Database | Details |
|---|---|---|
| Ptr 723 | Tyr 723 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 84733.4 | |
| All* | Total formula weight | 84733.4 |
