1A1R

HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NS3 PROTEIN	polymer	198	21045.0	2	UniProt (P27958) Pfam (PF02907)	Hepatitis C virus
2	C, D (C, D)	NS4A PROTEIN	polymer	23	2394.0	2	UniProt (P27958) Pfam (PF01006) UniProt (by SIFTS) (O39914)	Hepatitis C virus
3	E, F (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	G, H, I, J (A, B, C, D)	water	water		18.0	130	Chemie (HOH)

Sequence modifications

A, B: 22 - 206 (UniProt: P27958)

PDB	External Database	Details
Gln 23	Trp 1023	conflict
Gln 24	Arg 1024	conflict
Met 25	Leu 1025	conflict
Gly 26	Leu 1026	conflict
Met 100	Thr 1100	variant

C, D: 21 - 39 (UniProt: P27958)

PDB	External Database	Details
Ser 22	Cys 1679	variant

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	46878.0
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	47008.8

*Water molecules are not included.