1A0H
THE X-RAY CRYSTAL STRUCTURE OF PPACK-MEIZOTHROMBIN DESF1: KRINGLE/THROMBIN AND CARBOHYDRATE/KRINGLE/THROMBIN INTERACTIONS AND LOCATION OF THE LINKER CHAIN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | MEIZOTHROMBIN | polymer | 159 | 17868.3 | 2 | UniProt (P00735) Pfam (PF00051) Pfam (PF09396) | Bos taurus (cattle) | DESF1 |
| 2 | B, D (B, E) | MEIZOTHROMBIN | polymer | 259 | 29772.4 | 2 | UniProt (P00735) Pfam (PF00089) | Bos taurus (cattle) | DESF1 |
| 3 | E, F (C, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, H (B, E) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 2 | BIRD (PRD_000020) Chemie (0G6) | PPACK | ||
| 5 | I, J, K, L (A, B, D, E) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A, D: 164 - 320 (UniProt: P00735)
| PDB | External Database | Details |
|---|---|---|
| His 187 | Ser 231 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 95281.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 908.0 | |
| All* | Total formula weight | 97038.3 |
