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1XDK

Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Retinoic acid receptor RXR-alphapolymer23826579.72UniProt (P28700)
Pfam (PF00104)
Mus musculus (house mouse)
2B, F
(B, F)
Retinoic acid receptor, betapolymer30333978.12UniProt (P22605)
Pfam (PF00104)
Mus musculus (house mouse)RAR-beta
3C, D, G, H
(C, D, G, H)
Thyroid Receptor Associated Protein 220polymer141609.94UniProt (Q8BX19)
UniProt (by SIFTS) (Q925J9)
TRAP220
4I, J, K, L
(A, B, E, F)
(9cis)-retinoic acidnon-polymer300.44Chemie (9CR)
5M, N, O, P
(A, B, E, F)
waterwater18.012Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight127555.3
Non-Polymers*Number of molecules4
Total formula weight1201.7
All*Total formula weight128757.1
*Water molecules are not included.

242842

PDB entries from 2025-10-08

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