13HA

The structure of Fab_C1 in complex with CD30

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	FabS1CE2_C1 heavy chain	polymer	227	24214.2	1		Homo sapiens
2	B (C)	FabS1CE2_C1 light chain (Trastuzumab Fab Light Chain)	polymer	212	23225.7	1		Homo sapiens
3	C (A)	Tumor necrosis factor receptor superfamily member 8	polymer	101	11263.8	1	UniProt (P28908)	Homo sapiens (human)	CD30L receptor,Ki-1 antigen,Lymphocyte activation antigen CD30
4	D, E, F, G, H... (B, C)	1,2-ETHANEDIOL	non-polymer		62.1	11	Chemie (EDO)
5	L, M, N, O, U... (B, C)	CHLORIDE ION	non-polymer		35.5	7	Chemie (CL) PubChem (312)
6	P, X, Y (B, C)	SODIUM ION	non-polymer		23.0	3	Chemie (NA) PubChem (923)
7	S (C)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG) PubChem (8117)
8	AA, BA, Z (C, A, B)	water	water		18.0	536	Chemie (HOH)

Sequence modifications

A: 66 - 153 (UniProt: P28908)

PDB	External Database	Details
Gln 65	-	expression tag
Leu 154	-	expression tag
Val 155	-	expression tag
Pro 156	-	expression tag
Arg 157	-	expression tag
Gly 158	-	expression tag
Ser 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	58703.7
Non-Polymers*	Number of molecules	22
	Total formula weight	1106.0
All*	Total formula weight	59809.7

*Water molecules are not included.