12UQ
BCL11B ZF2-3 in Complex with a DNA Sequence Containing Two Binding Sites (Motifs TGTCCC and TGGCCT)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Strand Top | polymer | 20 | 6077.9 | 1 | Homo sapiens | ||
| 2 | B (B) | Strand Bottom | polymer | 20 | 6194.0 | 1 | Homo sapiens | ||
| 3 | C, D (F, C) | B-cell lymphoma/leukemia 11B | polymer | 66 | 7390.6 | 2 | UniProt (Q9C0K0) | Homo sapiens (human) | BCL-11B,B-cell CLL/lymphoma 11B,COUP-TF-interacting protein 2,Radiation-induced tumor suppressor gene 1 protein,hRit1 |
| 4 | E, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | F (A) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) PubChem (81462) | |||
| 6 | I, J (B) | UNKNOWN LIGAND | non-polymer | 65.4 | 2 | Chemie (UNX) | |||
| 7 | K, L, M, N (F, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) PubChem (32051) | |||
| 8 | O, P (A, B) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
F, C: 423 - 483 (UniProt: Q9C0K0)
| PDB | External Database | Details |
|---|---|---|
| Gly 418 | - | expression tag |
| Pro 419 | - | expression tag |
| Leu 420 | - | expression tag |
| Gly 421 | - | expression tag |
| Ser 422 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 27053.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 787.9 | |
| All* | Total formula weight | 27841.1 |
