12IY
Locally refined cryo-EM structure of human cannabinoid receptor 2 with agonist '5249
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Cannabinoid receptor 2 | polymer | 374 | 41442.4 | 1 | UniProt (P34972) | Homo sapiens (human) | CB-2,CB2,hCB2,CX5 |
| 2 | B (R) | (3R)-3-{2-oxo-2-[7-(trifluoromethyl)-3,4-dihydro-1,5-benzoxazepin-5(2H)-yl]ethyl}-2-benzofuran-1(3H)-one | non-polymer | 391.3 | 1 | Chemie (A1DB5) |
Sequence modifications
R: 1 - 360 (UniProt: P34972)
| PDB | External Database | Details |
|---|---|---|
| Asp -13 | - | expression tag |
| Tyr -12 | - | expression tag |
| Lys -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41442.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 391.3 | |
| All* | Total formula weight | 41833.7 |
