12GT
HDAC1-MTA1 in complex with WNA0 (7-(dimethylamino)-1-(5-(thiophen-2-yl)isoxazol-3-yl)heptan-1-one), a nonhydrolyzable analog of WNA1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Metastasis-associated protein MTA1 | polymer | 195 | 22165.8 | 1 | UniProt (Q13330) | Homo sapiens (human) | |
| 2 | B (B) | Histone deacetylase 1 | polymer | 482 | 55178.9 | 1 | UniProt (Q13547) | Homo sapiens (human) | HD1,Protein deacetylase HDAC1,Protein decrotonylase HDAC1 |
| 3 | C, E, H (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | D, K, L (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 5 | F (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 6 | G (B) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 7 | I, J (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 8 | M (B) | 7-(dimethylamino)-1-[5-(thiophen-2-yl)-1,2-oxazol-3-yl]heptan-1-one | non-polymer | 306.4 | 1 | Chemie (A1DB2) | |||
| 9 | N, O (A, B) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A: 162 - 354 (UniProt: Q13330)
| PDB | External Database | Details |
|---|---|---|
| Gly 160 | - | expression tag |
| Ala 161 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77344.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 989.7 | |
| All* | Total formula weight | 78334.4 |
