12EM
Crystal structure of a B1,3-Glucosyltransferase (B3GLCT) reveals an unusual mode of substrate recognition by a two-domain GT-A fold glycosyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-1,3-glucosyltransferase | polymer | 433 | 49371.4 | 1 | UniProt (Q6Y288) | Homo sapiens (human) | Beta3Glc-T,Beta 3-glucosyltransferase,Beta-3-glycosyltransferase-like |
| 2 | B (B) | Thrombospondin-1 | polymer | 61 | 6568.4 | 1 | UniProt (P07996) | Homo sapiens (human) | Glycoprotein G |
| 3 | C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) PubChem (27854) | |||
| 4 | D (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 5 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) PubChem (24139) | |||
| 6 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 7 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | H (B) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) PubChem (439554) | |||
| 9 | I, J (A, B) | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence modifications
B: 9 - 67 (UniProt: P07996)
| PDB | External Database | Details |
|---|---|---|
| Asp 8 | - | expression tag |
| Leu 68 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55939.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 998.6 | |
| All* | Total formula weight | 56938.4 |
