12AG
Spermine-blocked open-state cryo-EM structure of human TRPV6 channel in cNW30 nanodiscs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily V member 6 | polymer | 612 | 70019.6 | 4 | UniProt (Q9H1D0) | Homo sapiens (human) | TrpV6,CaT-like,CaT-L,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2 |
| 2 | BA, DA, E, EA, F... (D, A, B, C) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 12 | Chemie (Y01) PubChem (65082) | |||
| 3 | FA, G, P, X (D, A, B, C) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 4 | Chemie (PCW) | |||
| 4 | AA, CA, GA, H, I... (D, A, B, C) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 12 | Chemie (POV) | |||
| 5 | S (B) | SPERMINE | non-polymer | 202.3 | 1 | Chemie (SPM) PubChem (1103) | |||
| 6 | HA, IA, JA, KA (A, B, C, D) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 280078.3 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 18312.4 | |
| All* | Total formula weight | 298390.7 |
