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12AD

Structure of mammalian Type 2 Inositol 1,4,5-trisphosphate receptors (IP3R2) in the Apo-state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2polymer2701307853.84UniProt (Q9Z329)Mus musculus (house mouse)IP3 receptor isoform 2,IP3R 2,InsP3R2,Inositol 1,4,5-trisphosphate receptor type 2,5-trisphosphate type V receptor,Type 2 inositol 1,5-trisphosphate receptor,Type 2 InsP3 receptor
2E, L, R, Y
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
3AA, BA, F, G, H...
(D, A, B, C)
(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOLnon-polymer767.120Chemie (PLX)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight1231415.0
Non-Polymers*Number of molecules24
Total formula weight15604.3
All*Total formula weight1247019.3
*Water molecules are not included.

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PDB entries from 2026-07-29

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