10GH
Cryo-EM structure of Receptor Tyrosine Kinase ROS1 in complex with Fab-RX5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase ROS | polymer | 1006 | 112553.8 | 1 | UniProt (Q78DX7) | Mus musculus (house mouse) | Proto-oncogene c-Ros,Proto-oncogene c-Ros-1,Receptor tyrosine kinase c-ros oncogene 1,c-Ros receptor tyrosine kinase |
| 2 | B (B) | Fab-RX5 light chain | polymer | 230 | 25079.7 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | Fab-RX5 heavy chain | polymer | 238 | 25503.3 | 1 | Homo sapiens (human) | ||
| 4 | D, E, F (E, D, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 5 | G, H, I, J, K (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 163136.8 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 165516.1 |
