10EI

GH33 sialidase from Alistipes dispar in complex with free sialic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	exo-alpha-sialidase	polymer	388	41988.2	1	UniProt (A0A4Y1WXT9) Pfam (PF13088)	Alistipes dispar
2	B (A)	N-acetyl-alpha-neuraminic acid	non-polymer		309.3	1	Chemie (SIA) PubChem (444885)
3	C, D (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL) PubChem (753)
4	E (A)	water	water		18.0	294	Chemie (HOH)

Sequence modifications

A: 20 - 385 (UniProt: A0A4Y1WXT9)

PDB	External Database	Details
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
Ser 4	-	expression tag
Ser 5	-	expression tag
Gly 6	-	expression tag
Val 7	-	expression tag
Asp 8	-	expression tag
Leu 9	-	expression tag
Gly 10	-	expression tag
Thr 11	-	expression tag
Glu 12	-	expression tag
Asn 13	-	expression tag
Leu 14	-	expression tag
Tyr 15	-	expression tag
Phe 16	-	expression tag
Gln 17	-	expression tag
Ser 18	-	expression tag
Asn 19	-	expression tag
Asp 166	Asn 166	conflict
Arg 299	His 299	conflict
Gln 326	Arg 326	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41988.2
Non-Polymers*	Number of molecules	3
	Total formula weight	493.5
All*	Total formula weight	42481.7

*Water molecules are not included.