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10AK

Crystal Structure of Human WRN helicase with compound 4

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRNpolymer43149106.61UniProt (Q14191)Homo sapiens (human)DNA helicase,RecQ-like type 3,RecQ protein-like 2,Werner syndrome protein
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
N-benzyl-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]-2-[4-(1H-pyrrol-1-yl)phenyl]acetamidenon-polymer408.51Chemie (A1C4L)
4D, E
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
5F, G, H, I
(A)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
6J
(A)
waterwater18.0459Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49106.6
Non-Polymers*Number of molecules8
Total formula weight793.1
All*Total formula weight49899.7
*Water molecules are not included.

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PDB entries from 2026-05-13

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