5F4N

Multi-parameter lead optimization to give an oral CHK1 inhibitor clinical candidate: (R)-5-((4-((morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)

Chains

Entity	Asym IDs	Number of Exact matches
1	A	89

Click on a chain to show homologues chains within the PDB.

Click on an exact match to show the superposition between a chain and a match.

248942

PDB entries from 2026-02-11