Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000077 | biological_process | DNA damage checkpoint signaling |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue 5UY A 301 |
| Chain | Residue |
| A | LEU15 |
| A | GLU91 |
| A | GLU134 |
| A | LEU137 |
| A | SER147 |
| A | ASP148 |
| A | HOH521 |
| A | ALA36 |
| A | LYS38 |
| A | VAL68 |
| A | LEU84 |
| A | GLU85 |
| A | TYR86 |
| A | CYS87 |
| A | SER88 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue 5UY A 302 |
| Chain | Residue |
| A | TRP9 |
| A | VAL35 |
| A | VAL37 |
| A | TYR71 |
| A | PHE83 |
| A | HOH590 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | LEU179 |
| A | SER212 |
| A | ASP213 |
| A | HOH478 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | GLY123 |
| A | ARG156 |
| A | HOH482 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ASP209 |
| A | SER212 |
| A | SER214 |
| A | CYS215 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | LEU206 |
| A | TRP208 |
| A | ASP209 |
| A | HOH428 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 307 |
| Chain | Residue |
| A | TRP221 |
| A | LYS224 |
| A | HIS243 |
| A | LEU246 |
| A | HOH416 |
| A | HOH491 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 308 |
| Chain | Residue |
| A | PHE93 |
| A | ILE96 |
| A | PRO133 |
| A | TYR173 |
| A | GLY204 |
| A | GLU205 |
| A | LEU206 |
| A | HOH596 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAYGEVQlAvnrvteea..........VAVK |
| Chain | Residue | Details |
| A | LEU15-LYS38 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ItHrDIKpeNLLL |
| Chain | Residue | Details |
| A | ILE126-LEU138 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | ASP130 | |
| Chain | Residue | Details |
| A | LEU15 | |
| A | LYS38 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:32357935 |
| Chain | Residue | Details |
| A | LYS132 | |
