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8XT2
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BU of 8xt2 by Molmil
Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline
Descriptor: 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XT0
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BU of 8xt0 by Molmil
Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline
Descriptor: 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8QRN
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BU of 8qrn by Molmil
mt-SSU in GTPBP8 knock-out cells, state 4
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8QRM
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BU of 8qrm by Molmil
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8QRL
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BU of 8qrl by Molmil
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 2
Descriptor: 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8QRK
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BU of 8qrk by Molmil
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 1
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (6.69 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8OM4
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BU of 8om4 by Molmil
Small subunit of yeast mitochondrial ribosome.
Descriptor: 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ...
Authors:Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A.
Deposit date:2023-03-31
Release date:2024-01-10
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.32 Å)
Cite:METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Mol.Cell, 84, 2024
8OM3
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BU of 8om3 by Molmil
Small subunit of yeast mitochondrial ribosome in complex with IF3/Aim23.
Descriptor: 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ...
Authors:Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A.
Deposit date:2023-03-31
Release date:2024-01-10
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Mol.Cell, 84, 2024
8OM2
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BU of 8om2 by Molmil
Small subunit of yeast mitochondrial ribosome in complex with METTL17/Rsm22.
Descriptor: 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ...
Authors:Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A.
Deposit date:2023-03-31
Release date:2024-01-10
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Mol.Cell, 84, 2024
8OIS
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BU of 8ois by Molmil
28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA
Descriptor: 12S rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-06-14
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
8OIR
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BU of 8oir by Molmil
55S human mitochondrial ribosome with mtRF1 and P-site tRNA
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-06-14
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
8OIP
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BU of 8oip by Molmil
28S mammalian mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA
Descriptor: 12S rRNA, 28S ribosomal protein S15, mitochondrial, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-05-24
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
8OIN
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BU of 8oin by Molmil
55S mammalian mitochondrial ribosome with mtRF1 and P-site tRNA
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S15, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-06-14
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
8K2A
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BU of 8k2a by Molmil
Cryo-EM structure of the human 55S mitoribosome with Tigecycline
Descriptor: 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2023-07-12
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8D8L
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BU of 8d8l by Molmil
Yeast mitochondrial small subunit assembly intermediate (State 3)
Descriptor: 15S ribosomal RNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ...
Authors:Burnside, C, Harper, N, Klinge, S.
Deposit date:2022-06-08
Release date:2022-12-14
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature, 614, 2023
8D8K
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BU of 8d8k by Molmil
Yeast mitochondrial small subunit assembly intermediate (State 2)
Descriptor: 15S ribosomal RNA, 37S ribosomal protein MRP1, mitochondrial, ...
Authors:Burnside, C, Harper, N.J, Klinge, S.
Deposit date:2022-06-08
Release date:2022-12-21
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature, 614, 2023
8CSU
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BU of 8csu by Molmil
Human mitochondrial small subunit assembly intermediate (State C*)
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Harper, N.J, Burnside, C, Klinge, S.
Deposit date:2022-05-13
Release date:2022-12-14
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature, 614, 2023
8CST
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BU of 8cst by Molmil
Human mitochondrial small subunit assembly intermediate (State E)
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Harper, N.J, Burnside, C, Klinge, S.
Deposit date:2022-05-13
Release date:2022-12-14
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature, 614, 2023
8CSS
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BU of 8css by Molmil
Human mitochondrial small subunit assembly intermediate (State D)
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Harper, N.J, Burnside, C, Klinge, S.
Deposit date:2022-05-13
Release date:2022-12-14
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature, 614, 2023
8CSR
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BU of 8csr by Molmil
Human mitochondrial small subunit assembly intermediate (State C)
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Harper, N.J, Burnside, C, Klinge, S.
Deposit date:2022-05-13
Release date:2022-12-14
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature, 614, 2023
8CSQ
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BU of 8csq by Molmil
Human mitochondrial small subunit assembly intermediate (State B)
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Harper, N.J, Burnside, C, Klinge, S.
Deposit date:2022-05-13
Release date:2022-12-14
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature, 614, 2023
8CSP
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BU of 8csp by Molmil
Human mitochondrial small subunit assembly intermediate (State A)
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Harper, N.J, Burnside, C, Klinge, S.
Deposit date:2022-05-13
Release date:2022-12-14
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature, 614, 2023
8ANY
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BU of 8any by Molmil
Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA
Descriptor: 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ...
Authors:Singh, V, Itoh, Y, Amunts, A.
Deposit date:2022-08-06
Release date:2023-08-16
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome.
Nat.Struct.Mol.Biol., 2024
7QI6
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BU of 7qi6 by Molmil
Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution
Descriptor: 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ...
Authors:Singh, V, Itoh, Y, Amunts, A.
Deposit date:2021-12-14
Release date:2023-05-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
Nat Commun, 15, 2024
7QI5
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BU of 7qi5 by Molmil
Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A resolution
Descriptor: 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ...
Authors:Singh, V, Itoh, Y, Amunts, A.
Deposit date:2021-12-14
Release date:2023-07-05
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
Nat Commun, 15, 2024

 

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