1FWK
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP
Descriptor:HOMOSERINE KINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Zhou, T., Daugherty, M., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2000-09-22
Release date:2000-12-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
1FWL
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE
Descriptor:HOMOSERINE KINASE
Authors:Zhou, T., Daugherty, M., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2000-09-22
Release date:2000-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
1H72
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE
Descriptor:HOMOSERINE KINASE, L-HOMOSERINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Krishna, S.S., Zhou, T., Daugherty, M., Osterman, A.L., Zhang, H.
Deposit date:2001-07-02
Release date:2001-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
1H73
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH THREONINE
Descriptor:HOMOSERINE KINASE, THREONINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Krishna, S.S., Zhou, T., Daugherty, M., Osterman, A.L., Zhang, H.
Deposit date:2001-07-02
Release date:2001-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
1H74
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE
Descriptor:HOMOSERINE KINASE, ISOLEUCINE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Krishna, S.S., Zhou, T., Daugherty, M., Osterman, A.L., Zhang, H.
Deposit date:2001-07-02
Release date:2001-11-28
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
1KKH
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CRYSTAL STRUCTURE OF THE METHANOCOCCUS JANNASCHII MEVALONATE KINASE
Descriptor:Mevalonate Kinase, 1,4-DIETHYLENE DIOXIDE
Authors:Yang, D., Shipman, L.W., Roessner, C.A., Scott, A.I., Sacchettini, J.C.
Deposit date:2001-12-08
Release date:2002-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily.
J.Biol.Chem., 277, 2002
1KVK
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THE STRUCTURE OF BINARY COMPLEX BETWEEN A MAMMALIAN MEVALONATE KINASE AND ATP: INSIGHTS INTO THE REACTION MECHANISM AND HUMAN INHERITED DISEASE
Descriptor:mevalonate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Fu, Z., Wang, M., Potter, D., Mizioko, H.M., Kim, J.J.
Deposit date:2002-01-26
Release date:2002-03-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
1OJ4
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TERNARY COMPLEX OF 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE
Descriptor:4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Miallau, L., Alphey, M.S., Hunter, W.N.
Deposit date:2003-06-30
Release date:2003-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase
Proc.Natl.Acad.Sci.USA, 100, 2003
1PIE
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CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS GALACTOKINASE COMPLEXED WITH GALACTOSE
Descriptor:Galactokinase, ALPHA D-GALACTOSE, PHOSPHATE ION
Authors:Thoden, J.B., Holden, H.M.
Deposit date:2003-05-30
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular Structure of Galactokinase
J.Biol.Chem., 278, 2003
1S4E
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PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM
Descriptor:Galactokinase, ALPHA D-GALACTOSE, MAGNESIUM ION, ...
Authors:Hartley, A., Glynn, S.E., Barynin, V., Baker, P.J., Sedelnikova, S.E., Verhees, C., de Geus, D., van der Oost, J., Timson, D.J., Reece, R.J., Rice, D.W.
Deposit date:2004-01-16
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase
J.Mol.Biol., 337, 2004
1UEK
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CRYSTAL STRUCTURE OF 4-(CYTIDINE 5'-DIPHOSPHO)-2C-METHYL-D-ERYTHRITOL KINASE
Descriptor:4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase
Authors:Wada, T., Kuramitsu, S., Yokoyama, S., Tame, J.R.H., Park, S.Y., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-17
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, an Enzyme in the Non-mevalonate Pathway of Isoprenoid Synthesis.
J.Biol.Chem., 278, 2003
1VIS
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CRYSTAL STRUCTURE OF MEVALONATE KINASE
Descriptor:Mevalonate kinase, 1,4-DIETHYLENE DIOXIDE
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1WUU
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CRYSTAL STRUCTURE OF HUMAN GALACTOKINASE COMPLEXED WITH MGAMPPNP AND GALACTOSE
Descriptor:Galactokinase, ALPHA D-GALACTOSE, MAGNESIUM ION, ...
Authors:Thoden, J.B., Timson, D.J., Reece, R.J., Holden, H.M.
Deposit date:2004-12-08
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Structure of Human Galactokinase: IMPLICATIONS FOR TYPE II GALACTOSEMIA
J.Biol.Chem., 280, 2005
2A2C
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X-RAY STRUCTURE OF HUMAN N-ACETYL GALACTOSAMINE KINASE COMPLEXED WITH MG-ADP AND N-ACETYL GALACTOSAMINE 1-PHOSPHATE
Descriptor:N-acetylgalactosamine kinase, N-ACETYL-ALPHA-D-GALACTOSAMINE 1-PHOSPHATE, MAGNESIUM ION, ...
Authors:Thoden, J.B., Holden, H.M.
Deposit date:2005-06-22
Release date:2005-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The molecular architecture of human N-acetylgalactosamine kinase.
J.Biol.Chem., 280, 2005
2A2D
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X-RAY STRUCTURE OF HUMAN N-ACETYL GALACTOSAMINE KINASE COMPLEXED WITH MN-AMPPNP AND N-ACETYL GLACTOSAMINE
Descriptor:N-acetylgalactosamine kinase, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, MANGANESE (II) ION, ...
Authors:Thoden, J.B., Holden, H.M.
Deposit date:2005-06-22
Release date:2005-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular architecture of human N-acetylgalactosamine kinase.
J.Biol.Chem., 280, 2005
2AJ4
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CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE GALACTOKINASE IN COMPLEX WITH GALACTOSE AND MG:AMPPNP
Descriptor:Galactokinase, ALPHA D-GALACTOSE, MAGNESIUM ION, ...
Authors:Thoden, J.B., Sellick, C.A., Timson, D.J., Reece, R.J., Holden, H.M.
Deposit date:2005-08-01
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer
J.Biol.Chem., 280, 2005
2CZ9
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CRYSTAL STRUCTURE OF GALACTOKINASE FROM PYROCOCCUS HORIKOSHI
Descriptor:Probable galactokinase, CHLORIDE ION, GLYCEROL
Authors:Inagaki, E., Sakamoto, K., Shinkai, A., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-12
Release date:2006-09-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of galactokinase from Pyrococcus horikoshi
To be Published
2DEI
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CRYSTAL STRUCTURE OF GALAKTOKINASE FROM PYROCOCCUS HORIKOSHII WITH AMP-PNP AND GALACTOSE
Descriptor:Probable galactokinase, ALPHA D-GALACTOSE, MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE
Authors:Inagaki, E., Sakamoto, K., Shinkai, A., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-02-10
Release date:2007-05-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of galaktokinase from Pyrococcus horikoshii
To be Published
2DEJ
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CRYSTAL STRUCTURE OF GALAKTOKINASE FROM PYROCOCCUS HORIKOSHII WITH AMP-PN AND GALACTOSE
Descriptor:Probable galactokinase, ALPHA D-GALACTOSE, {5'-O-[(R)-{[(S)-AMINO(HYDROXY-KAPPAO)PHOSPHORYL]OXY}(HYDROXY-KAPPAO)PHOSPHORYL]ADENOSINATO(2-)}MAGNESIUM
Authors:Inagaki, E., Sakamoto, K., Shinkai, A., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-02-10
Release date:2007-05-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of galaktokinase from Pyrococcus horikoshii
To be Published
2HFS
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CRYSTAL STRUCTURE OF L. MAJOR MEVALONATE KINASE
Descriptor:Mevalonate kinase, putative
Authors:Sgraja, T., Hunter, W.N.
Deposit date:2006-06-26
Release date:2007-04-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase.
Bmc Struct.Biol., 7, 2007
2HFU
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CRYSTAL STRUCTURE OF L. MAJOR MEVALONATE KINASE IN COMPLEX WITH R-MEVALONATE
Descriptor:Mevalonate kinase, putative, (R)-MEVALONATE
Authors:Sgraja, T., Hunter, W.N.
Deposit date:2006-06-26
Release date:2007-04-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase.
Bmc Struct.Biol., 7, 2007
2OI2
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STREPTOCOCCUS PNEUMONIAE MEVALONATE KINASE IN COMPLEX WITH DIPHOSPHOMEVALONATE
Descriptor:Mevalonate kinase, MAGNESIUM ION, (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID
Authors:Andreassi, J.L., Bilder, P.W., Vetting, M.W., Roderick, S.L., Leyh, T.S.
Deposit date:2007-01-10
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate.
Protein Sci., 16, 2007
2R3V
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THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM
Descriptor:Mevalonate kinase
Authors:Fu, Z., Voynova, N.E., Miziorko, H.M., Kim, J.P.
Deposit date:2007-08-30
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
2R42
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THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM
Descriptor:Mevalonate kinase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
Authors:Fu, Z., Voynova, N.E., Miziorko, H.M., Kim, J.P.
Deposit date:2007-08-30
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
2WW4
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A TRICLINIC CRYSTAL FORM OF E. COLI 4-DIPHOSPHOCYTIDYL-2C-METHYL-D- ERYTHRITOL KINASE
Descriptor:4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL
Authors:Kalinowska-Tluscik, J., Miallau, L., Gabrielsen, M., Leonard, G.A., McSweeney, S.M., Hunter, W.N.
Deposit date:2009-10-21
Release date:2010-03-09
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Triclinic Crystal Form of Escherichia Coli 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase and Reassessment of the Quaternary Structure.
Acta Crystallogr.,Sect.F, 66, 2010
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