1PCI
| PROCARICAIN | Descriptor: | PROCARICAIN | Authors: | Groves, M.R, Taylor, M.A.J, Scott, M, Cummings, N.J, Pickersgill, R.W, Jenkins, J.A. | Deposit date: | 1996-06-28 | Release date: | 1997-04-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The prosequence of procaricain forms an alpha-helical domain that prevents access to the substrate-binding cleft. Structure, 4, 1996
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1CJL
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7PCK
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1BY8
| THE CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN K | Descriptor: | PROTEIN (PROCATHEPSIN K) | Authors: | Lalonde, J.M, Zhao, B, Smith, W.W, Janson, C.A, Desjarlais, R.L, Tomaszek, T.A, Carr, T.J, Thompson, S.K, Yamashita, D.S, Veber, D.F, Abdel-Mequid, S.S. | Deposit date: | 1998-10-27 | Release date: | 1999-10-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The crystal structure of human procathepsin K. Biochemistry, 38, 1999
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1CS8
| CRYSTAL STRUCTURE OF PROCATHEPSIN L | Descriptor: | HUMAN PROCATHEPSIN L | Authors: | Cygler, M, Coulombe, R. | Deposit date: | 1999-08-17 | Release date: | 1999-08-23 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment. EMBO J., 15, 1996
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2C0Y
| THE CRYSTAL STRUCTURE OF A CYS25ALA MUTANT OF HUMAN PROCATHEPSIN S | Descriptor: | PROCATHEPSIN S | Authors: | Kaulmann, G, Palm, G.J, Schilling, K, Hilgenfeld, R, Wiederanders, B. | Deposit date: | 2005-09-08 | Release date: | 2006-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of a Cys25 -> Ala Mutant of Human Procathepsin S Elucidates Enzyme-Prosequence Interactions. Protein Sci., 15, 2006
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2O6X
| Crystal Structure of ProCathepsin L1 from Fasciola hepatica | Descriptor: | Secreted cathepsin L 1 | Authors: | Brinen, L.S, Dalton, J.P, Geiger, S, Marion, R, Stack, C.M. | Deposit date: | 2006-12-08 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica. J.Biol.Chem., 283, 2008
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3F75
| Activated Toxoplasma gondii cathepsin L (TgCPL) in complex with its propeptide | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ... | Authors: | Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | Deposit date: | 2008-11-07 | Release date: | 2008-11-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl. J.Biol.Chem., 284, 2009
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3QJ3
| Structure of digestive procathepsin L2 proteinase from Tenebrio molitor larval midgut | Descriptor: | ACETATE ION, Cathepsin L-like protein | Authors: | Beton, D, Guzzo, C.R, Terra, W.R, Farah, C.S. | Deposit date: | 2011-01-28 | Release date: | 2012-02-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut. Insect Biochem.Mol.Biol., 42, 2012
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2L95
| Solution Structure of Cytotoxic T-Lymphocyte Antigent-2(Ctla protein), Crammer at pH 6.0 | Descriptor: | Crammer | Authors: | Tseng, T.S, Cheng, C.S, Liu, Y.N, Lyu, P.C. | Deposit date: | 2011-01-31 | Release date: | 2011-12-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin. Biochem.J., 442, 2012
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3QT4
| Structure of digestive procathepsin L 3 of Tenebrio molitor larval midgut | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Cathepsin-L-like midgut cysteine proteinase, PHOSPHATE ION, ... | Authors: | Beton, D, Guzzo, C.R, Terra, W.R, Farah, C.S. | Deposit date: | 2011-02-22 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut. Insect Biochem.Mol.Biol., 42, 2012
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3TNX
| Structure of the precursor of a thermostable variant of papain at 2.6 Angstroem resolution | Descriptor: | CHLORIDE ION, Papain | Authors: | Roy, S, Choudhury, D, Dattagupta, J.K, Biswas, S. | Deposit date: | 2011-09-02 | Release date: | 2012-09-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | The structure of a thermostable mutant of pro-papain reveals its activation mechanism Acta Crystallogr.,Sect.D, 68, 2012
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3USV
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4QRG
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4QRV
| Crystal structure of I86F mutant of papain | Descriptor: | CHLORIDE ION, Papain, SODIUM ION | Authors: | Dutta, S, Choudhury, D, Roy, S. | Deposit date: | 2014-07-02 | Release date: | 2015-08-12 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.978 Å) | Cite: | Pro-peptide regulates the substrate specificity and zymogen activation process of papain: A structural and mechanistic insight to be published
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4QRX
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5EF4
| 2.05 A crystal structure of the Amb a 11 cysteine protease, a major ragweed pollen allergen, in its proform | Descriptor: | Cysteine protease, GLYCEROL | Authors: | Briozzo, P, Kopecny, D, Savko, M. | Deposit date: | 2015-10-23 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and Functional Characterization of the Major Allergen Amb a 11 from Short Ragweed Pollen. J.Biol.Chem., 291, 2016
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5EGW
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5JT8
| Structural basis for the limited antibody cross reactivity between the mite allergens Blo t 1 and Der p 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Blo t 1 allergen, ... | Authors: | Meno, K, Kastrup, J.S, Gajhede, M. | Deposit date: | 2016-05-09 | Release date: | 2017-05-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of the mite allergen Blo t 1 explains the limited antibody cross-reactivity to Der p 1. Allergy, 72, 2017
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5Z5O
| Structure of Pycnonodysostosis disease related I249T mutant of human cathepsin K | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Biswas, S, Roy, S. | Deposit date: | 2018-01-19 | Release date: | 2018-09-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Not all pycnodysostosis-related mutants of human cathepsin K are inactive - crystal structure and biochemical studies of an active mutant I249T. FEBS J., 285, 2018
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6CZS
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6CZK
| Crystal structure of wild-type human pro-cathepsin H | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Pro-cathepsin H, ... | Authors: | Huang, X, Hao, Y. | Deposit date: | 2018-04-09 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Crystal structures of human procathepsin H. PLoS ONE, 13, 2018
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6JD0
| Structure of mutant human cathepsin L, engineered for GAG binding | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Cathepsin L1, ... | Authors: | Choudhury, D, Biswas, S. | Deposit date: | 2019-01-30 | Release date: | 2020-02-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.805 Å) | Cite: | Structure-guided protein engineering of human cathepsin L for efficient collagenolytic activity. Protein Eng.Des.Sel., 34, 2021
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6JD8
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6U7D
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