1HTR
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CRYSTAL AND MOLECULAR STRUCTURES OF HUMAN PROGASTRICSIN AT 1.62 ANGSTROMS RESOLUTION
Descriptor:PROGASTRICSIN (PRO SEGMENT), GASTRICSIN
Authors:Moore, S.A., Sielecki, A.R., James, M.N.G.
Deposit date:1994-10-21
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal and molecular structures of human progastricsin at 1.62 A resolution.
J.Mol.Biol., 247, 1995
1TZS
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CRYSTAL STRUCTURE OF AN ACTIVATION INTERMEDIATE OF CATHEPSIN E
Descriptor:Cathepsin E, activation peptide from Cathepsin E, 23-mer peptide from PelB-IgG kappa light chain fusion protein
Authors:Ostermann, N., Gerhartz, B., Worpenberg, S., Trappe, J., Eder, J.
Deposit date:2004-07-12
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of an activation intermediate of cathepsin e
J.Mol.Biol., 342, 2004
2PSG
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REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION
Descriptor:PEPSINOGEN
Authors:James, M.N.G., Sielecki, A.R.
Deposit date:1991-01-23
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined structure of porcine pepsinogen at 1.8 A resolution.
J.Mol.Biol., 219, 1991
2X0B
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CRYSTAL STRUCTURE OF HUMAN ANGIOTENSINOGEN COMPLEXED WITH RENIN
Descriptor:RENIN, ANGIOTENSINOGEN
Authors:Zhou, A., Wei, Z., Yan, Y., Carrell, R.W., Read, R.J.
Deposit date:2009-12-08
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.33 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
3PSG
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF PORCINE PEPSINOGEN
Descriptor:PEPSINOGEN
Authors:Hartsuck, J.A., Koelsch, G., Remington, S.J.
Deposit date:1991-09-03
Release date:1993-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The high-resolution crystal structure of porcine pepsinogen.
Proteins, 13, 1992
3VCM
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CRYSTAL STRUCTURE OF HUMAN PRORENIN
Descriptor:prorenin, N-ACETYL-D-GLUCOSAMINE
Authors:Morales, R., Watier, Y., Bocskei, Z.
Deposit date:2012-01-04
Release date:2012-05-23
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Human Prorenin Structure Sheds Light on a Novel Mechanism of Its Autoinhibition and on Its Non-Proteolytic Activation by the (Pro)renin Receptor.
J.Mol.Biol., 421, 2012
4AMT
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CRYSTAL STRUCTURE AT 2.6A OF HUMAN PRORENIN
Descriptor:RENIN, SULFATE ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhou, A.
Deposit date:2012-03-13
Release date:2013-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of Prorenin
To be Published
5MKT
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CRYSTAL STRUCTURE OF MOUSE PRORENIN
Descriptor:Renin-1, N-ACETYL-D-GLUCOSAMINE
Authors:Yan, Y., Read, R.
Deposit date:2016-12-05
Release date:2017-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of mouse prorenin
To Be Published
5N7N
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CRYSTAL STRUCTURE OF CATHEPSIN D ZYMOGEN FROM THE TICK IXODES RICINUS (IRCD1)
Descriptor:Putative cathepsin d, SULFATE ION, AMMONIUM ION
Authors:Brynda, J., Hanova, I., Hobizalova, R., Mares, M.
Deposit date:2017-02-21
Release date:2017-12-27
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Cell Chem Biol, 25, 2018
5UX4
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CRYSTAL STRUCTURE OF RAT CATHEPSIN D WITH (5S)-3-(5,6-DIHYDRO-2H-PYRAN-3-YL)-1-FLUORO- 7-(2-FLUOROPYRIDIN-3-YL)SPIRO[CHROMENO[2,3- C]PYRIDINE-5,4'-[1,3]OXAZOL]-2'-AMINE
Descriptor:Cathepsin D, N-ACETYL-D-GLUCOSAMINE, (5S)-3-(5,6-dihydro-2H-pyran-3-yl)-1-fluoro-7-(2-fluoropyridin-3-yl)spiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine
Authors:Sickmier, A.
Deposit date:2017-02-22
Release date:2018-06-13
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Development of 2-aminooxazoline 3-azaxanthene beta-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin D.
Medchemcomm, 8, 2017
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