6BAC
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CRYSTAL STRUCTURE OF ASPARTATE-SEMIALDEHYDE DEHYDROGENASE FROM NEISSERIA GONORRHOEAE
Descriptor:Aspartate-semialdehyde dehydrogenase, SULFATE ION, 1,2-ETHANEDIOL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-10-12
Release date:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Aspartate-Semialdehyde Dehydrogenase from Neisseria gonorrhoeae
to be published
5JW6
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CYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE FROM ASPERGILLUS FUMIGATUS
Descriptor:Aspartate-semialdehyde dehydrogenase, SULFATE ION
Authors:Dahal, G.P., Viola, R.E.
Deposit date:2016-05-11
Release date:2017-01-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5EIO
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CRYSTAL STRUCTURE OF LYSY FROM THERMUS THERMOPHILUS COMPLEXED WITH NADP+ AND LYSW-GAMMA-AMINOADIPIC SEMIALDEHYDE
Descriptor:N-acetyl-gamma-glutamyl-phosphate/N-acetyl-gamma-aminoadipyl-phosphate reductase, OrfF, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Shimizu, T., Tomita, T., Nishiyama, M.
Deposit date:2015-10-30
Release date:2016-03-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the LysYLysW Complex from Thermus thermophilus.
J.Biol.Chem., 291, 2016
5EIN
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CRYSTAL STRUCTURE OF C148A MUTANT OF LYSY FROM THERMUS THERMOPHILUS IN COMPLEX WITH NADP+ AND LYSW-GAMMA-AMINOADIPIC ACID
Descriptor:N-acetyl-gamma-glutamyl-phosphate/N-acetyl-gamma-aminoadipyl-phosphate reductase, OrfF, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Shimizu, T., Tomita, T., Nishiyama, M.
Deposit date:2015-10-30
Release date:2016-03-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the LysYLysW Complex from Thermus thermophilus.
J.Biol.Chem., 291, 2016
5CEF
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CYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE FROM CRYPTOCOCCUS NEOFORMANS
Descriptor:Aspartate-semialdehyde dehydrogenase, 1,2-ETHANEDIOL
Authors:Dahal, G.P., Viola, R.E.
Deposit date:2015-07-06
Release date:2015-11-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a fungal form of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans.
Acta Crystallogr.,Sect.F, 71, 2015
5BNT
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X-RAY CRYSTAL STRUCTURE OF A ASPARTATE-SEMIALDEHYDE DEHYDROGENASE BOUND TO NADP FROM PSEUDOMONAS AERUGINOSA
Descriptor:Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-05-26
Release date:2015-06-10
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Crystal Structure of a Aspartate-semialdehyde dehydrogenase bound to NADP from Pseudomonas aeruginosa
to be published
4ZIC
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE WITH NADP FROM TRICHOPHYTON RUBRUM
Descriptor:Aspartate Semialdehyde Dehydrogenase, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Li, Q., Cui, S.
Deposit date:2015-04-28
Release date:2016-03-02
Method:X-RAY DIFFRACTION (2.553 Å)
Cite:Structural Insights into the Tetrameric State of Aspartate-beta-semialdehyde Dehydrogenases from Fungal Species
Sci Rep, 6, 2016
4ZHS
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE FROM TRICHOPHYTON RUBRUM
Descriptor:Aspartate Semialdehyde Dehydrogenase, SULFATE ION
Authors:Li, Q., Cui, S.
Deposit date:2015-04-27
Release date:2016-03-02
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Structural Insights into the Tetrameric State of Aspartate-beta-semialdehyde Dehydrogenases from Fungal Species
Sci Rep, 6, 2016
4WOJ
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ASPARTATE SEMIALDEHYDE DEHYDROGENASE FROM FRANCISELLA TULARENSIS
Descriptor:Aspartate semialdehyde dehydrogenase, SULFATE ION, SODIUM ION
Authors:Mank, N.J., Arnette, A.K., Klapper, V.G., Chruszcz, M.
Deposit date:2014-10-15
Release date:2015-10-21
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of aspartate b-semialdehyde dehydrogenase from Francisella tularensis
Acta Crystallogr.,Sect.F, 74, 2018
4R5M
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CRYSTAL STRUCTURE OF VC-ASPARTATE BETA-SEMIALDEHYDE-DEHYDROGENASE WITH NADP AND 4-NITRO-2-PHOSPHONO-BENZOIC ACID
Descriptor:Aspartate-semialdehyde dehydrogenase 1, SODIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Pavlovsky, A.G., Thangavelu, B., Bhansali, P., Viola, R.E.
Deposit date:2014-08-21
Release date:2014-12-10
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4R3N
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CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF SP-ASADH WITH NADP AND 1,2,3-BENZENETRICARBOXYLIC ACID
Descriptor:Aspartate-semialdehyde dehydrogenase, SODIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Pavlovsky, A.G., Viola, R.E.
Deposit date:2014-08-16
Release date:2014-12-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4DPM
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STRUCTURE OF MALONYL-COENZYME A REDUCTASE FROM CRENARCHAEOTA IN COMPLEX WITH COA
Descriptor:Malonyl-CoA/succinyl-CoA reductase, MAGNESIUM ION, COENZYME A
Authors:Demmer, U., Warkentin, E., Srivastava, A., Kockelkorn, D., Fuchs, G., Ermler, U.
Deposit date:2012-02-13
Release date:2012-12-26
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for a Bispecific NADP+ and CoA Binding Site in an Archaeal Malonyl-Coenzyme A Reductase.
J.Biol.Chem., 288, 2013
4DPL
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STRUCTURE OF MALONYL-COENZYME A REDUCTASE FROM CRENARCHAEOTA IN COMPLEX WITH NADP
Descriptor:Malonyl-CoA/succinyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UNKNOWN LIGAND
Authors:Demmer, U., Warkentin, E., Srivastava, A., Kockelkorn, D., Fuchs, G., Ermler, U.
Deposit date:2012-02-13
Release date:2013-01-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for a Bispecific NADP+ and CoA Binding Site in an Archaeal Malonyl-Coenzyme A Reductase.
J.Biol.Chem., 288, 2013
4DPK
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STRUCTURE OF MALONYL-COENZYME A REDUCTASE FROM CRENARCHAEOTA
Descriptor:Malonyl-CoA/succinyl-CoA reductase, PHOSPHATE ION
Authors:Demmer, U., Warkentin, E., Srivastava, A., Kockelkorn, D., Fuchs, G., Ermler, U.
Deposit date:2012-02-13
Release date:2012-12-26
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Basis for a Bispecific NADP+ and CoA Binding Site in an Archaeal Malonyl-Coenzyme A Reductase.
J.Biol.Chem., 288, 2013
3VOS
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE COMPLEXED WITH GLYCEROL AND SULFATE FROM MYCOBACTERIUM TUBERCULOSIS H37RV
Descriptor:Aspartate-semialdehyde dehydrogenase, GLYCEROL, SULFATE ION
Authors:Vyas, R., Tewari, R., Weiss, M.S., Karthikeyan, S.
Deposit date:2012-02-07
Release date:2012-05-30
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv
Acta Crystallogr.,Sect.D, 68, 2012
3UW3
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CRYSTAL STRUCTURE OF AN ASPARTATE-SEMIALDEHYDE DEHYDROGENASE FROM BURKHOLDERIA THAILANDENSIS
Descriptor:Aspartate-semialdehyde dehydrogenase, 1,2-ETHANEDIOL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-11-30
Release date:2011-12-14
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
3TZ6
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE COMPLEXED WITH INHIBITOR SMCS (CYS) AND PHOSPHATE FROM MYCOBACTERIUM TUBERCULOSIS H37RV
Descriptor:Aspartate-semialdehyde dehydrogenase, CYSTEINE, GLYCEROL, ...
Authors:Vyas, R., Tewari, R., Weiss, M.S., Karthikeyan, S.
Deposit date:2011-09-27
Release date:2012-05-30
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv
Acta Crystallogr.,Sect.D, 68, 2012
3Q1L
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CRYSTALS STRUCTURE OF ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE FROM STREPTOCOCCUS PNEUMONIAE WITH CYSTEAMINE BOUND COVALENTLY TO CYS 128
Descriptor:Aspartate beta-semialdehyde dehydrogenase, 2-AMINO-ETHANETHIOL
Authors:Pavlovsky, A.G., Viola, R.E.
Deposit date:2010-12-17
Release date:2012-01-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012
3Q0E
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CRYSTALS STRUCTURE OF ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE FROM VIBRIO CHOLERAE WITH PRODUCT OF S-ALLYL-L-CYSTEINE SULFOXIDE
Descriptor:Aspartate-semialdehyde dehydrogenase, CYSTEINE, SULFATE ION, ...
Authors:Pavlovsky, A.G., Liu, X., Viola, R.E.
Deposit date:2010-12-15
Release date:2012-02-22
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of inhibitors with selectivity against members of a homologous enzyme family.
Chem.Biol.Drug Des., 79, 2012
3PZR
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CRYSTALS STRUCTURE OF ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE FROM VIBRIO CHOLERAE WITH NADP AND PRODUCT OF S-CARBAMOYL-L-CYSTEINE
Descriptor:Aspartate-semialdehyde dehydrogenase, CYSTEINE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Pavlovsky, A.G., Potente, N., Viola, R.E.
Deposit date:2010-12-14
Release date:2012-01-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012
3HSK
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE WITH NADP FROM CANDIDA ALBICANS
Descriptor:Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Arachea, B.T., Pavlovsky, A., Liu, X., Viola, R.E.
Deposit date:2009-06-10
Release date:2010-02-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog.
Acta Crystallogr.,Sect.D, 66, 2010
3DR3
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STRUCTURE OF IDP00107, A POTENTIAL N-ACETYL-GAMMA-GLUTAMYLPHOSPHATE REDUCTASE FROM SHIGELLA FLEXNERI
Descriptor:N-acetyl-gamma-glutamyl-phosphate reductase, SODIUM ION, D-MALATE
Authors:Singer, A.U., Skarina, T., Onopriyenko, O., Edwards, A.M., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2008-07-10
Release date:2008-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of IDP00107, a potential N-acetyl-gamma-glutamylphosphate reductase from Shigella flexneri
To be Published
2YV3
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8
Descriptor:Aspartate-semialdehyde dehydrogenase
Authors:Kagawa, W., Fujikawa, N., Kurumizaka, H., Bessho, Y., Ellis, M.J., Antonyuk, S.V., Strange, R.W., Hasnain, S.S., Kuramitsu, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-07
Release date:2007-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Thermus thermophilus HB8
To be Published
2R00
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE II COMPLEXED WITH ASA FROM VIBRIO CHOLERAE
Descriptor:Aspartate-semialdehyde dehydrogenase, 2,2'-oxydiacetic acid
Authors:Viola, R.E., Liu, X., Ohren, J.F., Faehnle, C.R.
Deposit date:2007-08-17
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
2QZ9
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE II FROM VIBRIO CHOLERAE
Descriptor:Aspartate-semialdehyde dehydrogenase
Authors:Viola, R.E., Liu, X., Ohren, J.F., Faehnle, C.R.
Deposit date:2007-08-16
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
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