6D1Q
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CRYSTAL STRUCTURE OF E. COLI RPPH-DAPF COMPLEX, MONOMER
Descriptor:Diaminopimelate epimerase, RNA pyrophosphohydrolase, CHLORIDE ION, ...
Authors:Gao, A., Serganov, A.
Deposit date:2018-04-12
Release date:2018-05-23
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF.
Nucleic Acids Res., 46, 2018
6D1V
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CRYSTAL STRUCTURE OF E. COLI RPPH-DAPF COMPLEX, MONOMER BOUND TO RNA
Descriptor:Diaminopimelate epimerase, RNA pyrophosphohydrolase, RNA (5'-D(*(APC))-R(P*GP*U)-3'), ...
Authors:Gao, A., Serganov, A.
Deposit date:2018-04-12
Release date:2018-05-23
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF.
Nucleic Acids Res., 46, 2018
6D13
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CRYSTAL STRUCTURE OF E.COLI RPPH-DAPF COMPLEX
Descriptor:Diaminopimelate epimerase, RNA pyrophosphohydrolase, IODIDE ION, ...
Authors:Gao, A., Serganov, A.
Deposit date:2018-04-11
Release date:2018-05-23
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF.
Nucleic Acids Res., 46, 2018
5YGU
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI (STRAIN K12) MRNA DECAPPING COMPLEX RPPH-DAPF
Descriptor:Diaminopimelate epimerase, RNA pyrophosphohydrolase, L(+)-TARTARIC ACID, ...
Authors:Wang, Q., Guan, Z.Y., Zhang, D.L., Zou, T.T., Yin, P.
Deposit date:2017-09-27
Release date:2018-06-06
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:DapF stabilizes the substrate-favoring conformation of RppH to stimulate its RNA-pyrophosphohydrolase activity in Escherichia coli.
Nucleic Acids Res., 46, 2018
5H2Y
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CRYSTAL STRCUTURE OF REDUCED DAPF FROM CORYNEBACTERIUM GLUTAMICUM
Descriptor:Diaminopimelate epimerase
Authors:Sagong, H.-Y., Kim, K.-J.
Deposit date:2016-10-18
Release date:2016-11-09
Last modified:2017-07-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for redox sensitivity in Corynebacterium glutamicum diaminopimelate epimerase: an enzyme involved in l-lysine biosynthesis.
Sci Rep, 7, 2017
5M47
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CRYSTAL STRCUTURE OF DAPF FROM CORYNEBACTERIUM GLUTAMICUM IN COMPLEX WITH D,L-DIAMINOPIMELATE
Descriptor:Diaminopimelate epimerase, 2,6-DIAMINOPIMELIC ACID
Authors:Sagong, H.-Y., Kim, K.-J.
Deposit date:2016-10-18
Release date:2016-11-02
Last modified:2017-07-19
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis for redox sensitivity in Corynebacterium glutamicum diaminopimelate epimerase: an enzyme involved in l-lysine biosynthesis.
Sci Rep, 7, 2017
5H2G
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CRYSTAL STRCUTURE OF OXIDIZED DAPF FROM CORYNEBACTERIUM GLUTAMICUM
Descriptor:Diaminopimelate epimerase, GLYCEROL, SULFATE ION
Authors:Sagong, H.-Y., Kim, K.-J.
Deposit date:2016-10-15
Release date:2016-11-09
Last modified:2017-07-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for redox sensitivity in Corynebacterium glutamicum diaminopimelate epimerase: an enzyme involved in l-lysine biosynthesis.
Sci Rep, 7, 2017
5HA4
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STRUCTURE OF A DIAMINOPIMELATE EPIMERASE FROM ACINETOBACTER BAUMANNII
Descriptor:Diaminopimelate epimerase, (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-12-30
Release date:2016-01-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of a diaminopimelate epimerase from Acinetobacter baumannii
to be published
4IJZ
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE FROM ESCHERICHIA COLI
Descriptor:Diaminopimelate epimerase, NITRATE ION
Authors:Hor, L., Dobson, R.C.J., Hutton, C.A., Perugini, M.A.
Deposit date:2012-12-24
Release date:2013-02-20
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
4IK0
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE Y268A MUTANT FROM ESCHERICHIA COLI
Descriptor:Diaminopimelate epimerase, IODIDE ION
Authors:Hor, L., Dobson, R.C.J., Hutton, C.A., Perugini, M.A.
Deposit date:2012-12-24
Release date:2013-02-20
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
3FVE
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE MYCOBACTERIUM TUBERCULOSIS DAPF
Descriptor:Diaminopimelate epimerase, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL
Authors:Usha, V., Dover, L.G., Roper, D.I., Futterer, K., Besra, G.S.
Deposit date:2009-01-15
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the diaminopimelate epimerase DapF from Mycobacterium tuberculosis
Acta Crystallogr.,Sect.D, 65, 2009
3EKM
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE FORM ARABIDOPSIS THALIANA IN COMPLEX WITH IRREVERSIBLE INHIBITOR DL-AZIDAP
Descriptor:Diaminopimelate epimerase, chloroplastic, (2R,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID
Authors:Pillai, B., Moorthie, V.A., Cherney, M.M., van Belkum, M.J., Vederas, J.C., James, M.N.G.
Deposit date:2008-09-19
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis.
J.Mol.Biol., 385, 2009
3EJX
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE FROM ARABIDOPSIS THALIANA IN COMPLEX WITH LL-AZIDAP
Descriptor:Diaminopimelate epimerase, chloroplastic, (2S,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID
Authors:Pillai, B., Moorthie, V.A., Cherney, M.M., Vederas, J.C., James, M.N.G.
Deposit date:2008-09-18
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis.
J.Mol.Biol., 385, 2009
2Q9H
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CRYSTAL STRUCTURE OF THE C73S MUTANT OF DIAMINOPIMELATE EPIMERASE
Descriptor:Diaminopimelate epimerase, L(+)-TARTARIC ACID, ACETIC ACID
Authors:Pillai, B., Cherney, M., Diaper, C.M., Sutherland, A., Blanchard, J.S., Vederas, J.C., James, M.N.G.
Deposit date:2007-06-12
Release date:2007-10-23
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.
Biochem.Biophys.Res.Commun., 363, 2007
2Q9J
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CRYSTAL STRUCTURE OF THE C217S MUTANT OF DIAMINOPIMELATE EPIMERASE
Descriptor:Diaminopimelate epimerase, SULFATE ION, 1,2-ETHANEDIOL
Authors:Pillai, B., Cherney, M., Diaper, C.M., Sutherland, A., Blanchard, J.S., Vederas, J.C.
Deposit date:2007-06-12
Release date:2007-10-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.
Biochem.Biophys.Res.Commun., 363, 2007
2OTN
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CRYSTAL STRUCTURE OF THE CATALYTICALLY ACTIVE FORM OF DIAMINOPIMELATE EPIMERASE FROM BACILLUS ANTHRACIS
Descriptor:Diaminopimelate epimerase
Authors:Matho, M.H., Fukuda, K., Santelli, E., Jaroszewski, L., Liddington, R.C., Roper, D.
Deposit date:2007-02-08
Release date:2008-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure and inhibition of a catalytically active form of diaminopimelate epimerase (DapF)from Bacillus anthracis
To be Published
2GKJ
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE IN COMPLEX WITH AN IRREVERSIBLE INHIBITOR DL-AZIDAP
Descriptor:Diaminopimelate epimerase, (2R,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, ACETIC ACID
Authors:Pillai, B., Cherney, M.M., Diaper, C.M., Sutherland, A., Blanchard, J.S., Vederas, J.C., James, M.N.
Deposit date:2006-04-02
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GKE
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE IN COMPLEX WITH AN IRREVERSIBLE INHIBITOR LL-AZIDAP
Descriptor:Diaminopimelate epimerase, (2S,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, GLYCEROL, ...
Authors:Pillai, B., Cherney, M.M., Diaper, C.M., Sutherland, A., Blanchard, J.S., Vederas, J.C., James, M.N.
Deposit date:2006-04-01
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1GQZ
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REFINEMENT OF HAEMOPHILUS INFLUENZAE DIAMINOPIMELATE EPIMERASE AT 1.7A
Descriptor:DIAMINOPIMELATE EPIMERASE
Authors:Roper, D.I., Huyton, T., Turkenburg, J.P.
Deposit date:2001-12-07
Release date:2003-06-12
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Refinement of Haemophilus influenzae diaminopimelic acid epimerase (DapF) at 1.75 A resolution suggests a mechanism for stereocontrol during catalysis.
Acta Crystallogr. D Biol. Crystallogr., 60, 2004
1BWZ
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DIAMINOPIMELATE EPIMERASE FROM HEMOPHILUS INFLUENZAE
Descriptor:PROTEIN (DIAMINOPIMELATE EPIMERASE)
Authors:Cirilli, M., Zheng, R., Scapin, G., Blanchard, J.S.
Deposit date:1998-09-29
Release date:1998-12-16
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural symmetry: the three-dimensional structure of Haemophilus influenzae diaminopimelate epimerase.
Biochemistry, 37, 1998
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