1BF3
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P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND ARG 42 REPLACED BY LYS (R42K), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1998-05-26
Release date:1998-08-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lys42 and Ser42 variants of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens reveal that Arg42 is essential for NADPH binding.
Eur.J.Biochem., 253, 1998
1BGJ
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P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND HIS 162 REPLACED BY ARG (H162R), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1998-05-29
Release date:1998-08-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants.
J.Biol.Chem., 273, 1998
1BGN
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P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND ARG 269 REPLACED BY THR (R269T), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1998-05-29
Release date:1998-08-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants.
J.Biol.Chem., 273, 1998
1BKW
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P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS116 REPLACED BY SER (C116S) AND ARG44 REPLACED BY LYS (R44K), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor:PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE), FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H., Schreuder, H.A., Van Berkel, W.J.
Deposit date:1998-07-13
Release date:1998-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and function of mutant Arg44Lys of 4-hydroxybenzoate hydroxylase implications for NADPH binding.
Eur.J.Biochem., 231, 1995
1CC4
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PHE161 AND ARG166 VARIANTS OF P-HYDROXYBENZOATE HYDROXYLASE. IMPLICATIONS FOR NADPH RECOGNITION AND STRUCTURAL STABILITY.
Descriptor:PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE), FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Bunthof, C., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1999-03-04
Release date:1999-03-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Phe161 and Arg166 variants of p-hydroxybenzoate hydroxylase. Implications for NADPH recognition and structural stability.
Febs Lett., 443, 1999
1CC6
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PHE161 AND ARG166 VARIANTS OF P-HYDROXYBENZOATE HYDROXYLASE. IMPLICATIONS FOR NADPH RECOGNITION AND STRUCTURAL STABILITY.
Descriptor:PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE), FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Bunthof, C., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1999-03-04
Release date:1999-03-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Phe161 and Arg166 variants of p-hydroxybenzoate hydroxylase. Implications for NADPH recognition and structural stability.
Febs Lett., 443, 1999
1CJ2
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MUTANT GLN34ARG OF PARA-HYDROXYBENZOATE HYDROXYLASE
Descriptor:PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE), FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Overkamp, K.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1999-04-21
Release date:1999-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Switch of coenzyme specificity of p-hydroxybenzoate hydroxylase.
J.Mol.Biol., 292, 1999
1CJ3
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MUTANT TYR38GLU OF PARA-HYDROXYBENZOATE HYDROXYLASE
Descriptor:PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE), FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Overkamp, K.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1999-04-21
Release date:1999-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Switch of coenzyme specificity of p-hydroxybenzoate hydroxylase.
J.Mol.Biol., 292, 1999
1CJ4
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MUTANT Q34T OF PARA-HYDROXYBENZOATE HYDROXYLASE
Descriptor:PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE), FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Overkamp, K.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1999-04-21
Release date:1999-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Switch of coenzyme specificity of p-hydroxybenzoate hydroxylase.
J.Mol.Biol., 292, 1999
1D7L
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STRUCTURE-FUNCTION CORRELATIONS OF THE REACTION OF REDUCED NICOTINAMIDE ANALOGS WITH P-HYDROXYBENZOATE HYDROXYLASE SUBSTITUTED WITH A SERIES OF 8-SUBSTITUTED FLAVINS
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, SULFATE ION, 8-DEMETHYL-8-DIMETHYLAMINO-FLAVIN-ADENINE-DINUCLEOTIDE, ...
Authors:Ortiz-Maldonado, M., Gatti, D., Ballou, D.P., Massey, V.
Deposit date:1999-10-18
Release date:2000-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-function correlations of the reaction of reduced nicotinamide analogues with p-hydroxybenzoate hydroxylase substituted with a series of 8-substituted flavins.
Biochemistry, 38, 1999
1DOB
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THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Gatti, D.L., Palfey, B.A., Lah, M.S., Entsch, B., Massey, V., Ballou, D.P., Ludwig, M.L.
Deposit date:1994-09-06
Release date:1994-11-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The mobile flavin of 4-OH benzoate hydroxylase.
Science, 266, 1994
1DOC
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THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Gatti, D.L., Palfey, B.A., Lah, M.S., Entsch, B., Massey, V., Ballou, D.P., Ludwig, M.L.
Deposit date:1994-09-06
Release date:1994-11-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The mobile flavin of 4-OH benzoate hydroxylase.
Science, 266, 1994
1DOD
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THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 2,4-DIHYDROXYBENZOIC ACID
Authors:Gatti, D.L., Palfey, B.A., Lah, M.S., Entsch, B., Massey, V., Ballou, D.P., Ludwig, M.L.
Deposit date:1994-09-06
Release date:1994-11-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The mobile flavin of 4-OH benzoate hydroxylase.
Science, 266, 1994
1DOE
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THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Gatti, D.L., Palfey, B.A., Lah, M.S., Entsch, B., Massey, V., Ballou, D.P., Ludwig, M.L.
Deposit date:1994-09-06
Release date:1994-11-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The mobile flavin of 4-OH benzoate hydroxylase.
Science, 266, 1994
1IUS
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P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE AT PH 5.0
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 4-AMINOBENZOIC ACID
Authors:Gatti, D.L., Entsch, B., Ballou, D.P., Ludwig, M.L.
Deposit date:1995-11-22
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:pH-dependent structural changes in the active site of p-hydroxybenzoate hydroxylase point to the importance of proton and water movements during catalysis.
Biochemistry, 35, 1996
1IUT
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P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE AT PH 7.4
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 4-AMINOBENZOIC ACID
Authors:Gatti, D.L., Entsch, B., Ballou, D.P., Ludwig, M.L.
Deposit date:1995-11-22
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:pH-dependent structural changes in the active site of p-hydroxybenzoate hydroxylase point to the importance of proton and water movements during catalysis.
Biochemistry, 35, 1996
1IUU
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P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE AT PH 9.4
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 4-AMINOBENZOIC ACID
Authors:Gatti, D.L., Entsch, B., Ballou, D.P., Ludwig, M.L.
Deposit date:1995-11-22
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:pH-dependent structural changes in the active site of p-hydroxybenzoate hydroxylase point to the importance of proton and water movements during catalysis.
Biochemistry, 35, 1996
1IUV
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P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-4-HYDROXYBENZOATE AT PH 5.0
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Gatti, D.L., Entsch, B., Ballou, D.P., Ludwig, M.L.
Deposit date:1995-11-22
Release date:1996-06-20
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:pH-dependent structural changes in the active site of p-hydroxybenzoate hydroxylase point to the importance of proton and water movements during catalysis.
Biochemistry, 35, 1996
1IUW
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P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-4-HYDROXYBENZOATE AT PH 7.4
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Gatti, D.L., Entsch, B., Ballou, D.P., Ludwig, M.L.
Deposit date:1995-11-22
Release date:1996-07-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:pH-dependent structural changes in the active site of p-hydroxybenzoate hydroxylase point to the importance of proton and water movements during catalysis.
Biochemistry, 35, 1996
1IUX
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P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-4-HYDROXYBENZOATE AT PH 9.4
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Gatti, D.L., Entsch, B., Ballou, D.P., Ludwig, M.L.
Deposit date:1995-11-22
Release date:1996-07-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:pH-dependent structural changes in the active site of p-hydroxybenzoate hydroxylase point to the importance of proton and water movements during catalysis.
Biochemistry, 35, 1996
1K0I
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PSEUDOMONAS AERUGINOSA PHBH R220Q IN COMPLEX WITH 100MM PHB
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, SULFATE ION, SULFITE ION, ...
Authors:Wang, J., Ortiz-Maldonado, M., Entsch, B., Ballou, D., Gatti, D.L.
Deposit date:2001-09-19
Release date:2002-02-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1K0J
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PSEUDOMONAS AERUGINOSA PHBH R220Q IN COMPLEX WITH NADPH AND FREE OF P-OHB
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, SULFATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Wang, J., Ortiz-Maldonado, M., Entsch, B., Ballou, D., Gatti, D.L.
Deposit date:2001-09-19
Release date:2002-02-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1K0L
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PSEUDOMONAS AERUGINOSA PHBH R220Q FREE OF P-OHB
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, SULFATE ION, SULFITE ION, ...
Authors:Wang, J., Ortiz-Maldonado, M., Entsch, B., Ballou, D., Gatti, D.L.
Deposit date:2001-09-19
Release date:2002-02-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1PBB
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CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 2,4-DIHYDROXYBENZOIC ACID
Authors:Schreuder, H.A., Mattevi, A., Hol, W.G.J.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PBC
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CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 2-HYDROXY-4-AMINOBENZOIC ACID
Authors:Schreuder, H.A., Van Der Bolt, F.J.T., Van Berkel, W.J.H.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
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