3C37
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X-RAY STRUCTURE OF THE PUTATIVE ZN-DEPENDENT PEPTIDASE Q74D82 AT THE RESOLUTION 1.7 A. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET GSR143A
Descriptor:Peptidase, M48 family, ZINC ION, ...
Authors:Kuzin, A.P., Chen, Y., Seetharaman, J., Vorobiev, S.M., Forouhar, F., Wang, D., Mao, L., Maglaqui, M., Xiao, R., Liu, J., Baran, M.C., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-01-27
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray structure of the putative Zn-dependent peptidase Q74D82 at the resolution 1.7 A.
To be Published
2YPT
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CRYSTAL STRUCTURE OF THE HUMAN NUCLEAR MEMBRANE ZINC METALLOPROTEASE ZMPSTE24 MUTANT (E336A) IN COMPLEX WITH A SYNTHETIC CSIM TETRAPEPTIDE FROM THE C-TERMINUS OF PRELAMIN A
Descriptor:CAAX PRENYL PROTEASE 1 HOMOLOG, PRELAMIN-A/C, ZINC ION
Authors:Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Savitsky, P., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.
Deposit date:2012-11-01
Release date:2012-12-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
4AW6
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CRYSTAL STRUCTURE OF THE HUMAN NUCLEAR MEMBRANE ZINC METALLOPROTEASE ZMPSTE24 (FACE1)
Descriptor:CAAX PRENYL PROTEASE 1 HOMOLOG, ZINC ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.
Deposit date:2012-05-31
Release date:2012-07-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
4IL3
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CRYSTAL STRUCTURE OF S. MIKATAE STE24P
Descriptor:Ste24p, ZINC ION
Authors:Pryor Jr., E.E., Horanyi, P.S., Clark, K., Fedoriw, N., Connelly, S.M., Koszelak-Rosenblum, M., Zhu, G., Malkowski, M.G., Dumont, M.E., Wiener, M.C., Membrane Protein Structural Biology Consortium (MPSBC)
Deposit date:2012-12-28
Release date:2013-02-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Structure of the integral membrane protein CAAX protease Ste24p.
Science, 339, 2013
5SYT
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CRYSTAL STRUCTURE OF ZMPSTE24
Descriptor:CAAX prenyl protease 1 homolog, SULFATE ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Clark, K., Jenkins, J.L., Fedoriw, N., Dumont, M.E., Membrane Protein Structural Biology Consortium (MPSBC)
Deposit date:2016-08-11
Release date:2016-11-02
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors.
Protein Sci., 26, 2017
6BH8
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CRYSTAL STRUCTURE OF ZMPSTE24 IN COMPLEX WITH PHOSPHORAMIDON
Descriptor:CAAX prenyl protease 1 homolog, ZINC ION, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ...
Authors:Goblirsch, B.R., Arachea, B.T., Wiener, M.C.
Deposit date:2017-10-30
Release date:2018-08-15
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24.
Acta Crystallogr D Struct Biol, 74, 2018
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