3EZU
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CRYSTAL STRUCTURE OF MULTIDOMAIN PROTEIN OF UNKNOWN FUNCTION WITH GGDEF-DOMAIN (NP_951600.1) FROM GEOBACTER SULFURREDUCENS AT 1.95 A RESOLUTION
Descriptor:GGDEF domain protein, UNKNOWN LIGAND, 1,2-ETHANEDIOL
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-10-23
Release date:2008-11-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of multidomain protein of unknown function with GGDEF-domain (NP_951600.1) from GEOBACTER SULFURREDUCENS at 1.95 A resolution
To be published
3HVA
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CRYSTAL STRUCTURE OF FIMX GGDEF DOMAIN FROM PSEUDOMONAS AERUGINOSA
Descriptor:Protein FimX
Authors:Navarro, M.V.A.S., De, N., Bae, N., Sondermann, H.
Deposit date:2009-06-15
Release date:2009-08-18
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.042 Å)
Cite:Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX.
Structure, 17, 2009
3IGN
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CRYSTAL STRUCTURE OF THE GGDEF DOMAIN FROM MARINOBACTER AQUAEOLEI DIGUANYLATE CYCLASE COMPLEXED WITH C-DI-GMP - NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MQR89A
Descriptor:Diguanylate cyclase, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
Authors:Vorobiev, S., Neely, H., Seetharaman, J., Wang, H., Foote, E.L., Ciccosanti, C., Sahdev, S., Xiao, R., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-07-28
Release date:2009-08-11
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of a catalytically active GG(D/E)EF diguanylate cyclase domain from Marinobacter aquaeolei with bound c-di-GMP product.
J.Struct.Funct.Genom., 13, 2012
3MTK
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X-RAY STRUCTURE OF DIGUANYLATE CYCLASE/PHOSPHODIESTERASE FROM CALDICELLULOSIRUPTOR SACCHAROLYTICUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CLR27C
Descriptor:Diguanylate cyclase/phosphodiesterase
Authors:Kuzin, A., Abashidze, M., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Wang, D., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-04-30
Release date:2010-06-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Northeast Structural Genomics Consortium Target ClR27C
To be Published
3QYY
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A NOVEL INTERACTION MODE BETWEEN A MICROBIAL GGDEF DOMAIN AND THE BIS-(3, 5 )-CYCLIC DI-GMP
Descriptor:Response regulator, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DI(HYDROXYETHYL)ETHER, ...
Authors:Yang, C.-Y., Chin, K.-H., Chou, S.-H.
Deposit date:2011-03-04
Release date:2011-11-30
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure and inhibition of a GGDEF diguanylate cyclase complexed with (c-di-GMP)(2) at the active site
Acta Crystallogr.,Sect.D, 67, 2011
3TVK
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DIGUANYLATE CYCLASE DOMAIN OF DGCZ
Descriptor:Diguanylate cyclase DgcZ, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, ...
Authors:Zaehringer, F., Schirmer, T.
Deposit date:2011-09-20
Release date:2012-10-03
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and signaling mechanism of a zinc-sensory diguanylate cyclase.
Structure, 21, 2013
4H54
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CRYSTAL STRUCTURE OF THE DIGUANYLATE CYCLASE DGCZ
Descriptor:Diguanylate cyclase YdeH, ZINC ION, GUANOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE, ...
Authors:Zaehringer, F., Schirmer, T.
Deposit date:2012-09-18
Release date:2013-07-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structure and signaling mechanism of a zinc-sensory diguanylate cyclase.
Structure, 21, 2013
4URS
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CRYSTAL STRUCTURE OF GGDEF DOMAIN FROM T.MARITIMA
Descriptor:DIGUANYLATE CYCLASE, GLYCEROL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Deepthi, A., Liew, C.W., Liang, Z.X., Swaminathan, K., Lescar, J.
Deposit date:2014-07-02
Release date:2014-10-08
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
4WXO
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SADC (300-487) FROM PSEUDOMONAS AERUGINOSA PAO1
Descriptor:Uncharacterized protein
Authors:Liu, C., Liu, S., Gu, L.
Deposit date:2014-11-14
Release date:2015-11-18
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Crystal structure of SadC (300-487) from Pseudomonas aeruginosa PAO1
To Be Published
4WXW
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SADC (323-487) FROM PSEUDOMONAS AERUGINOSA PAO1
Descriptor:Uncharacterized protein, MAGNESIUM ION
Authors:Liu, C., Liu, S., Gu, L.
Deposit date:2014-11-14
Release date:2015-11-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of SadC (323-487) from Pseudomonas aeruginosa PAO1
To Be Published
4ZMM
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GGDEF DOMAIN OF DCSBIS COMPLEXED WITH C-DI-GMP
Descriptor:diguanylate cyclase, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
Authors:Chen, Y., Liu, C., Liu, S., Chi, K., Gu, L.
Deposit date:2015-05-04
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Crystal structure of Dcsbis GGDEF domain complexed with c-di-GMP
To Be Published
5EUH
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CRYSTAL STRUCTURE OF THE C-DI-GMP-BOUND GGDEF DOMAIN OF P. FLUORESCENS GCBC
Descriptor:Putative GGDEF domain membrane protein, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), SULFATE ION
Authors:Giglio, K.M., Cooley, R.B., Sondermann, H.
Deposit date:2015-11-18
Release date:2015-12-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:Contribution of Physical Interactions to Signaling Specificity between a Diguanylate Cyclase and Its Effector.
Mbio, 6, 2015
4ZMU
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DCSBIS, A DIGUANYLATE CYCLASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:diguanylate cyclase
Authors:Chen, Y., Liu, C., Liu, S., Chi, K., Gu, L.
Deposit date:2015-05-04
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:crystal structure of Dcsbis from Pseudomonas aeruginosa
To Be Published
1W25
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RESPONSE REGULATOR PLED IN COMPLEX WITH C-DIGMP
Descriptor:STALKED-CELL DIFFERENTIATION CONTROLLING PROTEIN, ZINC ION, MAGNESIUM ION, ...
Authors:Chan, C., Schirmer, T., Jenal, U.
Deposit date:2004-06-28
Release date:2004-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Activity and Allosteric Control of Diguanylate Cyclase
Proc.Natl.Acad.Sci.USA, 101, 2004
2V0N
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ACTIVATED RESPONSE REGULATOR PLED IN COMPLEX WITH C-DIGMP AND GTP- ALPHA-S
Descriptor:RESPONSE REGULATOR PLED, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Wassmann, P., Schirmer, T.
Deposit date:2007-05-15
Release date:2007-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structure of Bef3--Modified Response Regulator Pled: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition
Structure, 15, 2007
2WB4
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ACTIVATED DIGUANYLATE CYCLASE PLED IN COMPLEX WITH C-DI-GMP
Descriptor:DIGUANYLATE CYCLASE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Wassmann, P., Schirmer, T.
Deposit date:2009-02-20
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Activated Pled, Identification of Dimerization and Catalysis Relevant Regulatory Mechanisms
To be Published
3BRE
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CRYSTAL STRUCTURE OF P.AERUGINOSA PA3702
Descriptor:Probable two-component response regulator, MAGNESIUM ION, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
Authors:De, N., Pirruccello, M., Krasteva, P.V., Bae, N., Raghavan, R.V., Sondermann, H.
Deposit date:2007-12-21
Release date:2008-04-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Phosphorylation-independent regulation of the diguanylate cyclase WspR.
Plos Biol., 6, 2008
3I5A
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CRYSTAL STRUCTURE OF FULL-LENGTH WPSR FROM PSEUDOMONAS SYRINGAE
Descriptor:Response regulator/GGDEF domain protein, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), STRONTIUM ION
Authors:Navarro, M.V.A.S., De, N., Sondermann, H.
Deposit date:2009-07-03
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.796 Å)
Cite:Determinants for the activation and autoinhibition of the diguanylate cyclase response regulator WspR.
J.Mol.Biol., 393, 2009
3PJW
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STRUCTURE OF PSEUDOMONAS FLUORESCENCE LAPD GGDEF-EAL DUAL DOMAIN, I23
Descriptor:Cyclic dimeric GMP binding protein
Authors:Sondermann, H., Navarro, M.V.A.S.
Deposit date:2010-11-10
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1006 Å)
Cite:Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis.
Plos Biol., 9, 2011
3PJX
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STRUCTURE OF PSEUDOMONAS FLUORESCENCE LAPD GGDEF-EAL DUAL DOMAIN, P32
Descriptor:Cyclic dimeric GMP binding protein, 1,2-ETHANEDIOL
Authors:Sondermann, H., Navarro, M.V.A.S.
Deposit date:2010-11-10
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.0002 Å)
Cite:Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis.
Plos Biol., 9, 2011
4J40
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CRYSTAL STRUCTURE OF THE DUAL-DOMAIN GGDEF-EAL MODULE OF FIMX FROM PSEUDOMONAS AERUGINOSA
Descriptor:FimX
Authors:Navarro, M.V., De, N., Bae, N., Wang, Q., Sondermann, H.
Deposit date:2013-02-06
Release date:2013-02-20
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX.
Structure, 17, 2009
4RNF
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PAMORA TANDEM DIGUANYLATE CYCLASE - MUTANT PHOSPHODIESTERASE, APO FORM
Descriptor:Motility regulator
Authors:Phippen, C.W., Tews, I.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
4RNH
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PAMORA TANDEM DIGUANYLATE CYCLASE - PHOSPHODIESTERASE, C-DI-GMP COMPLEX
Descriptor:Motility regulator, MAGNESIUM ION, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
Authors:Phippen, C.W., Tews, I.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
5LLW
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BACTERIOPHYTOCHROME ACTIVATED DIGUANYLYL CYCLASE FROM IDIOMARINA SPECIES A28L
Descriptor:Diguanylate cyclase (GGDEF) domain-containing protein, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, CHLORIDE ION
Authors:Gourinchas, G., Winkler, A.
Deposit date:2016-07-28
Release date:2017-03-15
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Long-range allosteric signaling in red light-regulated diguanylyl cyclases.
Sci Adv, 3, 2017
5LLX
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BACTERIOPHYTOCHROME ACTIVATED DIGUANYLYL CYCLASE FROM IDIOMARINA SPECIES A28L WITH GTP BOUND
Descriptor:Diguanylate cyclase (GGDEF) domain-containing protein, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, CHLORIDE ION, ...
Authors:Gourinchas, G., Winkler, A.
Deposit date:2016-07-28
Release date:2017-03-15
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Long-range allosteric signaling in red light-regulated diguanylyl cyclases.
Sci Adv, 3, 2017
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