8J9H
| Cryo-EM structure of Euglena gracilis respiratory complex I, deactive state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2023-05-03 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism. Nat Commun, 15, 2024
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8J9I
| Cryo-EM structure of Euglena gracilis complex I, turnover state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2023-05-03 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism. Nat Commun, 15, 2024
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8J9J
| Cryo-EM structure of Euglena gracilis complex I, NADH state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2023-05-03 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism. Nat Commun, 15, 2024
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7D3U
| Structure of Mrp complex from Dietzia sp. DQ12-45-1b | Descriptor: | Cation antiporter, DODECYL-BETA-D-MALTOSIDE, Monovalent Na+/H+ antiporter subunit A, ... | Authors: | Li, B, Zhang, K.D, Wu, X.L, Zhang, X.C. | Deposit date: | 2020-09-21 | Release date: | 2020-12-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the Dietzia Mrp complex reveals molecular mechanism of this giant bacterial sodium proton pump. Proc.Natl.Acad.Sci.USA, 117, 2020
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7AQW
| Cryo-EM structure of Arabidopsis thaliana Complex-I (membrane tip) | Descriptor: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Acyl carrier protein 1, mitochondrial, ... | Authors: | Klusch, N, Kuehlbrandt, W, Yildiz, O. | Deposit date: | 2020-10-23 | Release date: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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7ZKQ
| Early Pp module assembly intermediate of complex I | Descriptor: | CARDIOLIPIN, Complex I intermediate-associated protein 30-domain-containing protein, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Schiller, J, Laube, E, Vonck, J, Zickermann, V. | Deposit date: | 2022-04-13 | Release date: | 2022-11-23 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling. Sci Adv, 8, 2022
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8BEH
| Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane tip) | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | Authors: | Klusch, N, Kuehlbrandt, W. | Deposit date: | 2022-10-21 | Release date: | 2023-01-11 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (2.29 Å) | Cite: | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution. Nat.Plants, 9, 2023
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6Z16
| Structure of the Mrp antiporter complex | Descriptor: | Multisubunit Na+/H+ antiporter, A subunit, B subunit, ... | Authors: | Steiner, J, Sazanov, L.A. | Deposit date: | 2020-05-12 | Release date: | 2020-08-12 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter. Elife, 9, 2020
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4HE8
| Crystal structure of the membrane domain of respiratory complex I from Thermus thermophilus | Descriptor: | NADH-quinone oxidoreductase subunit 10, NADH-quinone oxidoreductase subunit 11, NADH-quinone oxidoreductase subunit 12, ... | Authors: | Baradaran, R, Berrisford, J.M, Minhas, G.S, Sazanov, L.A. | Deposit date: | 2012-10-03 | Release date: | 2013-02-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of the entire respiratory complex I. Nature, 494, 2013
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6I1P
| Respiratory complex I from Thermus thermophilus with bound NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | Authors: | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | Deposit date: | 2018-10-29 | Release date: | 2020-09-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.207 Å) | Cite: | Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
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6CFW
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5O31
| Mitochondrial complex I in the deactive state | Descriptor: | Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Blaza, J.N, Vinothkumar, K.R, Hirst, J. | Deposit date: | 2017-05-23 | Release date: | 2018-01-17 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (4.13 Å) | Cite: | Structure of the Deactive State of Mammalian Respiratory Complex I. Structure, 26, 2018
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6Y79
| Cryo-EM structure of a respiratory complex I F89A mutant | Descriptor: | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | Authors: | Parey, K. | Deposit date: | 2020-02-28 | Release date: | 2020-10-28 | Last modified: | 2021-02-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I. Nat Commun, 11, 2020
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4HEA
| Crystal structure of the entire respiratory complex I from Thermus thermophilus | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | Authors: | Baradaran, R, Berrisford, J.M, Minhas, G.S, Sazanov, L.A. | Deposit date: | 2012-10-03 | Release date: | 2013-02-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3027 Å) | Cite: | Crystal structure of the entire respiratory complex I. Nature, 494, 2013
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5XTD
| Cryo-EM structure of human respiratory complex I | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | Authors: | Gu, J, Wu, M, Yang, M. | Deposit date: | 2017-06-19 | Release date: | 2017-08-30 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
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5GUP
| Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1 | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | Authors: | Gu, J, Wu, M, Guo, R, Yang, M. | Deposit date: | 2016-08-30 | Release date: | 2017-03-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of Mammalian Respiratory Supercomplex I1III2IV1 Cell, 167, 2016
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7AK5
| Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yin, Z, Bridges, H.R, Grba, D, Hirst, J. | Deposit date: | 2020-09-29 | Release date: | 2021-02-03 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Structural basis for a complex I mutation that blocks pathological ROS production. Nat Commun, 12, 2021
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5GPN
| Architecture of mammalian respirasome | Descriptor: | Acyl carrier protein, COPPER (II) ION, Cytochrome b, ... | Authors: | Gu, J, Wu, M, Guo, R, Yang, M. | Deposit date: | 2016-08-03 | Release date: | 2017-04-05 | Last modified: | 2017-04-12 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | The architecture of the mammalian respirasome. Nature, 537, 2016
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7B0N
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7F9O
| PSI-NDH supercomplex of Barley | Descriptor: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | Authors: | Wang, W.D, Shen, L, Tang, K, Han, G.Y, Shen, J.R, Zhang, X. | Deposit date: | 2021-07-04 | Release date: | 2021-12-22 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Architecture of the chloroplast PSI-NDH supercomplex in Hordeum vulgare. Nature, 601, 2022
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7EU3
| Chloroplast NDH complex | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ... | Authors: | Wang, W.D, Shen, L, Tang, K, Han, G.Y, Zhang, X, Shen, J.R. | Deposit date: | 2021-05-15 | Release date: | 2021-12-29 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Architecture of the chloroplast PSI-NDH supercomplex in Hordeum vulgare. Nature, 601, 2022
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5XTH
| Cryo-EM structure of human respiratory supercomplex I1III2IV1 | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | Authors: | Gu, J, Wu, M, Yang, M. | Deposit date: | 2017-06-19 | Release date: | 2017-09-13 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
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5XTC
| Cryo-EM structure of human respiratory complex I transmembrane arm | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | Authors: | Gu, J, Wu, M, Yang, M. | Deposit date: | 2017-06-19 | Release date: | 2017-08-30 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
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8ESW
| Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Padavannil, A, Letts, J.A. | Deposit date: | 2022-10-15 | Release date: | 2023-03-29 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state. Elife, 12, 2023
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8ESZ
| Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state | Descriptor: | (2R)-3-{[(S)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Padavannil, A, Letts, J.A. | Deposit date: | 2022-10-15 | Release date: | 2023-03-29 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state. Elife, 12, 2023
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