1GAT
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SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR
Descriptor:DNA (5'-D(P*AP*GP*AP*TP*AP*AP*AP*C)3'), DNA (5'-D(P*GP*TP*TP*TP*AP*TP*CP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ...
Authors:Clore, G.M., Omichinski, J.G., Gronenborn, A.M.
Deposit date:1993-06-28
Release date:1993-10-31
Last modified:2012-09-05
Method:SOLUTION NMR
Cite:NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
Science, 261, 1993
1GAU
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SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR
Descriptor:DNA (5'-D(P*AP*GP*AP*TP*AP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*TP*AP*TP*CP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1
Authors:Clore, G.M., Omichinski, J.G., Gronenborn, A.M.
Deposit date:1993-06-28
Release date:1993-10-31
Last modified:2012-09-05
Method:SOLUTION NMR
Cite:NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
Science, 261, 1993
1GNF
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SOLUTION STRUCTURE OF THE N-TERMINAL ZINC FINGER OF MURINE GATA-1, NMR, 25 STRUCTURES
Descriptor:TRANSCRIPTION FACTOR GATA-1, ZINC ION
Authors:Kowalski, K., Czolij, R., King, G.F., Crossley, M., Mackay, J.P.
Deposit date:1998-10-12
Release date:1999-06-08
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG.
J.Biomol.NMR, 13, 1999
1Y0J
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ZINC FINGERS AS PROTEIN RECOGNITION MOTIFS: STRUCTURAL BASIS FOR THE GATA-1/FRIEND OF GATA INTERACTION
Descriptor:Erythroid transcription factor, Zinc-finger protein ush, ZINC ION
Authors:Liew, C.K., Simpson, R.J.Y., Kwan, A.H.Y., Crofts, L.A., Loughlin, F.E., Matthews, J.M., Crossley, M., Mackay, J.P.
Deposit date:2004-11-15
Release date:2005-01-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/Friend of GATA interaction
Proc.Natl.Acad.Sci.Usa, 102, 2005
2GAT
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SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE
Descriptor:DNA (5'-D(*GP*TP*TP*GP*CP*AP*GP*AP*TP*AP*AP*AP*CP*AP*TP*T)-3'), DNA (5'-D(*AP*AP*TP*GP*TP*TP*TP*AP*TP*CP*TP*GP*CP*AP*AP*C)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ...
Authors:Clore, G.M., Tjandra, N., Starich, M., Omichinski, J.G., Gronenborn, A.M.
Deposit date:1997-11-07
Release date:1998-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution.
Nat.Struct.Biol., 4, 1997
2M9W
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SOLUTION NMR STRUCTURE OF TRANSCRIPTION FACTOR GATA-4 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR4783B
Descriptor:Transcription factor GATA-4, ZINC ION
Authors:Xu, X., Eletsky, A., Lee, D., Kohn, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-06-20
Release date:2013-07-10
Method:SOLUTION NMR
Cite:Solution NMR Structure of a Transcription Factor GATA-4 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR4783B
To be Published
3DFV
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ADJACENT GATA DNA BINDING
Descriptor:DNA (5'-D(*DTP*DTP*DCP*DTP*DGP*DAP*DTP*DAP*DAP*DGP*DAP*DCP*DTP*DTP*DAP*DTP*DCP*DTP*DGP*DC)-3'), DNA (5'-D(*DAP*DAP*DGP*DCP*DAP*DGP*DAP*DTP*DAP*DAP*DGP*DTP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DG)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L., Kim, G.K., Guo, L., Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
3DFX
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OPPOSITE GATA DNA BINDING
Descriptor:DNA (5'-D(*DTP*DTP*DGP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DGP*DAP*DGP*DAP*DTP*DAP*DAP*DCP*DC)-3'), DNA (5'-D(*DAP*DAP*DGP*DGP*DTP*DTP*DAP*DTP*DCP*DTP*DCP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L., Kim, G.K., Guo, L., Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
3GAT
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SOLUTION NMR STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, 34 STRUCTURES
Descriptor:DNA (5'-D(*GP*TP*TP*GP*CP*AP*GP*AP*TP*AP*AP*AP*CP*AP*TP*T)-3'), DNA (5'-D(*AP*AP*TP*GP*TP*TP*TP*AP*TP*CP*TP*GP*CP*AP*AP*C)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ...
Authors:Clore, G.M., Tjandra, N., Starich, M., Omichinski, J.G., Gronenborn, A.M.
Deposit date:1997-11-07
Release date:1998-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution.
Nat.Struct.Biol., 4, 1997
3VD6
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BOTH ZN FINGERS OF GATA1 BOUND TO PALINDROMIC DNA RECOGNITION SITE, P21 CRYSTAL FORM
Descriptor:DNA (5'-D(*TP*TP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*TP*C)-3'), DNA (5'-D(*AP*AP*GP*AP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*C)-3'), Erythroid transcription factor, ...
Authors:Jacques, D.A., Ripin, N., Wilkinson-White, L.E., Guss, J.M., Matthews, J.M.
Deposit date:2012-01-04
Release date:2013-01-16
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:DNA recognition by GATA1 double finger
To be Published
3VEK
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BOTH ZN FINGERS OF GATA1 BOUND TO PALINDROMIC DNA RECOGNITION SITE, P1 CRYSTAL FORM
Descriptor:DNA (5'-D(*TP*TP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*TP*C)-3'), DNA (5'-D(*AP*AP*GP*AP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*C)-3'), Erythroid transcription factor, ...
Authors:Jacques, D.A., Ripin, N., Wilkinson-White, L.E., Guss, J.M., Matthews, J.M.
Deposit date:2012-01-09
Release date:2013-01-16
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:DNA recognition by GATA1 double finger
To be Published
4GAT
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SOLUTION NMR STRUCTURE OF THE WILD TYPE DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13BP DNA CONTAINING A CGATA SITE, REGULARIZED MEAN STRUCTURE
Descriptor:DNA (5'-D(*CP*AP*GP*CP*GP*AP*TP*AP*GP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*CP*GP*CP*TP*G)-3'), NITROGEN REGULATORY PROTEIN AREA, ...
Authors:Clore, G.M., Starich, M., Wikstrom, M., Gronenborn, A.M.
Deposit date:1997-11-07
Release date:1998-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of a fungal AREA protein-DNA complex: an alternative binding mode for the basic carboxyl tail of GATA factors.
J.Mol.Biol., 277, 1998
4HC7
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CRYSTAL STRUCTURE OF THE FULL DNA BINDING DOMAIN OF GATA3-COMPLEX 2
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HC9
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 3
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HCA
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 1
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
5GAT
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SOLUTION NMR STRUCTURE OF THE WILD TYPE DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13BP DNA CONTAINING A CGATA SITE, 35 STRUCTURES
Descriptor:DNA (5'-D(*CP*AP*GP*CP*GP*AP*TP*AP*GP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*CP*GP*CP*TP*G)-3'), NITROGEN REGULATORY PROTEIN AREA, ...
Authors:Clore, G.M., Starich, M., Wikstrom, M., Gronenborn, A.M.
Deposit date:1997-11-07
Release date:1998-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of a fungal AREA protein-DNA complex: an alternative binding mode for the basic carboxyl tail of GATA factors.
J.Mol.Biol., 277, 1998
6GAT
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SOLUTION NMR STRUCTURE OF THE L22V MUTANT DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13 BP DNA CONTAINING A TGATA SITE, REGULARIZED MEAN STRUCTURE
Descriptor:DNA (5'-D(*CP*AP*GP*TP*GP*AP*TP*AP*GP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*CP*AP*CP*TP*G)-3'), NITROGEN REGULATORY PROTEIN AREA, ...
Authors:Clore, G.M., Starich, M., Wikstrom, M., Gronenborn, A.M.
Deposit date:1997-11-07
Release date:1998-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity.
J.Mol.Biol., 277, 1998
7GAT
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SOLUTION NMR STRUCTURE OF THE L22V MUTANT DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13 BP DNA CONTAINING A TGATA SITE, 34 STRUCTURES
Descriptor:DNA (5'-D(*CP*AP*GP*TP*GP*AP*TP*AP*GP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*CP*AP*CP*TP*G)-3'), NITROGEN REGULATORY PROTEIN AREA, ...
Authors:Clore, G.M., Starich, M., Wikstrom, M., Gronenborn, A.M.
Deposit date:1997-11-07
Release date:1998-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity.
J.Mol.Biol., 277, 1998
2L6Y
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HADDOCK MODEL OF GATA1NF:LMO2LIM2-LDB1LID
Descriptor:Erythroid transcription factor, LIM domain only 2, linker, ...
Authors:Wilkinson-White, L., Gamsjaeger, R., Dastmalchi, S., Wienert, B., Stokes, P.H., Crossley, M., Mackay, J.P., Matthews, J.M.
Deposit date:2010-12-01
Release date:2011-08-31
Last modified:2011-09-28
Method:SOLUTION NMR
Cite:Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1
Proc.Natl.Acad.Sci.USA, 108, 2011
2L6Z
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HADDOCK MODEL OF GATA1NF:LMO2LIM2-LDB1LID WITH FOG
Descriptor:Erythroid transcription factor, Zinc finger protein ush, LIM domain only 2, ...
Authors:Wilkinson-White, L., Gamsjaeger, R., Dastmalchi, S., Wienert, B., Stokes, P.H., Crossley, M., Mackay, J.P., Matthews, J.M.
Deposit date:2010-12-01
Release date:2011-08-31
Last modified:2011-09-28
Method:SOLUTION NMR
Cite:Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1
Proc.Natl.Acad.Sci.USA, 108, 2011
2VUS
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CRYSTAL STRUCTURE OF UNLIGANDED NMRA-AREA ZINC FINGER COMPLEX
Descriptor:NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, SULFATE ION, ...
Authors:Kotaka, M., Johnson, C., Lamb, H.K., Hawkins, A.R., Ren, J., Stammers, D.K.
Deposit date:2008-05-30
Release date:2008-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area.
J.Mol.Biol., 381, 2008
2VUT
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CRYSTAL STRUCTURE OF NAD-BOUND NMRA-AREA ZINC FINGER COMPLEX
Descriptor:NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Kotaka, M., Johnson, C., Lamb, H.K., Hawkins, A.R., Ren, J., Stammers, D.K.
Deposit date:2008-05-30
Release date:2008-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area.
J.Mol.Biol., 381, 2008
2VUU
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CRYSTAL STRUCTURE OF NADP-BOUND NMRA-AREA ZINC FINGER COMPLEX
Descriptor:NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Kotaka, M., Johnson, C., Lamb, H.K., Hawkins, A.R., Ren, J., Stammers, D.K.
Deposit date:2008-05-30
Release date:2008-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area.
J.Mol.Biol., 381, 2008
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