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9B8U
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BU of 9b8u by Molmil
Crystal structure of CRX-Ret4 oligonucleotide complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Cone-rod homeobox protein, ...
Authors:Srivastava, D, Artemyev, N.O.
Deposit date:2024-04-01
Release date:2024-07-31
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular basis of CRX/DNA recognition and stoichiometry at the Ret4 response element.
Structure, 2024
9ANT
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BU of 9ant by Molmil
ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX
Descriptor: ANTENNAPEDIA HOMEODOMAIN, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
Authors:Fraenkel, E, Pabo, C.O.
Deposit date:1998-07-02
Release date:1998-10-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex.
Nat.Struct.Biol., 5, 1998
8T11
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BU of 8t11 by Molmil
Crystal structure of the PEG10 promoter-bound ONECUT2 R479A/R480A mutant DNA-binding domain
Descriptor: DNA (5'-D(P*AP*GP*AP*TP*CP*GP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*AP*AP*TP*CP*GP*AP*TP*CP*T)-3'), One cut domain family member 2
Authors:Chatterjee, A, Katiki, M, Murali, R.
Deposit date:2023-06-01
Release date:2024-08-28
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal structure of the PEG10 promoter-bound ONECUT2 R479A/R480A mutant DNA-binding domain
To Be Published
8T0F
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BU of 8t0f by Molmil
Crystal structure of the PEG10 promoter-bound ONECUT2 DNA-binding domain
Descriptor: DNA (5'-D(P*AP*GP*AP*TP*CP*GP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*AP*AP*TP*CP*GP*AP*TP*CP*T)-3'), One cut domain family member 2
Authors:Chatterjee, A, Katiki, M, Murali, R.
Deposit date:2023-05-31
Release date:2024-08-28
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structure of the PEG10 promoter-bound ONECUT2 DNA-binding domain
To Be Published
8SPU
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BU of 8spu by Molmil
Structure of ESRRB nucleosome bound OCT4 at site c
Descriptor: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2023-05-03
Release date:2023-06-28
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
8SPS
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BU of 8sps by Molmil
High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b
Descriptor: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2023-05-03
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
8PNC
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BU of 8pnc by Molmil
Transcription factor BARHL2 bound to TAAGT DNA sequence
Descriptor: BarH-like 2 homeobox protein, DNA
Authors:Morgunova, E, Popov, A, Yin, Y, Taipale, J.
Deposit date:2023-06-30
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Transcription factor BARHL2 bound to different DNA sequences
To Be Published
8PNA
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BU of 8pna by Molmil
transcription factor BARHL2 bound to TAATG DNA sequence
Descriptor: ACETATE ION, BarH-like 2 homeobox protein, DNA
Authors:Morgunova, E, Popov, A, Yin, Y, Taipale, J.
Deposit date:2023-06-30
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:transcription factor BARHL2 bound to different DNA sequences
To Be Published
8PN4
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BU of 8pn4 by Molmil
transcription factor BARHL2 bound to DNA sequences
Descriptor: ACETATE ION, BarH-like 2 homeobox protein, DNA
Authors:Morgunova, E, Yin, Y, Popov, A, Taipale, J.
Deposit date:2023-06-29
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:transcription factor BARHL2 bound to DNA sequences
To Be Published
8PMV
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BU of 8pmv by Molmil
transcription factor BARHL2 bound to TAAGC DNA sequence
Descriptor: BarH-like 2 homeobox protein, DNA
Authors:Morgunova, E, Popov, A, Yin, Y, Taipale, J.
Deposit date:2023-06-29
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:transcription factor BARHL2 bound to DNA sequences
To Be Published
8PMN
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BU of 8pmn by Molmil
transcription factor BARHL2 bound to DNA sequences
Descriptor: BarH-like 2 homeobox protein, DNA
Authors:Morgunova, E, Popov, A, Yin, Y, Taipale, J.
Deposit date:2023-06-29
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:transcription factor BARHL2 bound to DNA sequences
To Be Published
8PMF
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BU of 8pmf by Molmil
transcription factor BARHL2 bound to DNA sequences
Descriptor: BarH-like 2 homeobox protein, DNA
Authors:Morgunova, E, Popov, A, Yin, Y, Taipale, J.
Deposit date:2023-06-28
Release date:2024-07-10
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:transcription factor BARHL2 bound to DNA sequences
To Be Published
8PMC
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BU of 8pmc by Molmil
transcription factor BARHL2 bound to TAATT DNA sequence
Descriptor: BarH-like 2 homeobox protein, DNA
Authors:Morgunova, E, Popov, A, Yin, Y, Taipale, J.
Deposit date:2023-06-28
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:transcription factor BARHL2 bound to DNA sequences
To Be Published
8PM7
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BU of 8pm7 by Molmil
transcription factor BARHL2 bound to TAATC DNA sequence
Descriptor: BarH-like 2 homeobox protein, DNA
Authors:Morgunova, E, Popov, A, Yin, Y, Taipale, J.
Deposit date:2023-06-28
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:transcription factor BARHL2 bound to DNA sequences
To Be Published
8PM5
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BU of 8pm5 by Molmil
transcription factor BARHL2 bound to TAAAT DNA sequence
Descriptor: BarH-like 2 homeobox protein, DNA (5'-D(*AP*AP*CP*CP*AP*TP*TP*TP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*AP*AP*AP*TP*GP*GP*TP*T)-3')
Authors:Morgunova, E, Popov, A, Yin, Y, Taipale, J.
Deposit date:2023-06-28
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:transcription factor BARHL2 bound to DNA sequences
To Be Published
8P7G
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BU of 8p7g by Molmil
Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS
Descriptor: Paired mesoderm homeobox protein 2B
Authors:Russo, L, Diana, D, Fattorusso, R.
Deposit date:2023-05-30
Release date:2024-05-15
Last modified:2024-06-26
Method:SOLUTION NMR
Cite:Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS.
Chem Sci, 15, 2024
8OTS
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BU of 8ots by Molmil
OCT4 and MYC-MAX co-bound to a nucleosome
Descriptor: DNA (127-MER), Green fluorescent protein,POU domain, class 5, ...
Authors:Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N.
Deposit date:2023-04-21
Release date:2023-05-24
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
8OSB
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BU of 8osb by Molmil
TWIST1-TCF4-ALX4 complex on specific DNA
Descriptor: DNA (25-MER), Homeobox protein aristaless-like 4, Transcription factor 4, ...
Authors:Morgunova, E, Kim, S, Popov, A, Wysocka, J, Taipale, J.
Deposit date:2023-04-18
Release date:2024-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:DNA-guided transcription factor cooperativity shapes face and limb mesenchyme.
Cell, 187, 2024
8ILW
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BU of 8ilw by Molmil
Transcription factor LMX1a homeobox domain in complex with Pitx3 promoter
Descriptor: DNA (5'-D(*CP*AP*AP*CP*AP*CP*TP*TP*AP*AP*TP*CP*CP*AP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*TP*GP*GP*AP*TP*TP*AP*AP*GP*TP*GP*TP*T)-3'), LMX1A factor
Authors:Lv, M.Q, Lin, L.Q.
Deposit date:2023-03-04
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
8IKE
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BU of 8ike by Molmil
Transcription factors LMX1a mutant-R199A homeobox domain complex with Wnt1 promoter
Descriptor: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), LMX1A factor
Authors:Lv, M.Q, Lin, L.Q.
Deposit date:2023-02-28
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
8IK5
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BU of 8ik5 by Molmil
Transcription factor LMX1a homeobox domain in complex with Wnt1 promoter
Descriptor: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), GLYCEROL, ...
Authors:Lv, M.Q, Lin, L.Q.
Deposit date:2023-02-28
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.989 Å)
Cite:Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
8G8G
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BU of 8g8g by Molmil
Interaction of H3 tail in LIN28B nucleosome with Oct4
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
Deposit date:2023-02-17
Release date:2023-03-22
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8E
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BU of 8g8e by Molmil
Human Oct4 bound to nucleosome with human LIN28B sequence
Descriptor: LIN28B DNA (32-MER), POU domain, class 5, ...
Authors:Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
Deposit date:2023-02-17
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8B
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BU of 8g8b by Molmil
Nucleosome with human nMatn1 sequence in complex with Human Oct4
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
Deposit date:2023-02-17
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G88
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BU of 8g88 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
Deposit date:2023-02-17
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023

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