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8R7Q
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BU of 8r7q by Molmil
human connexin-36 gap junction channel in complex with quinine
Descriptor: Gap junction delta-2 protein, Quinine
Authors:Ding, X.Y, Blum, T.B, Korkhov, V.M.
Deposit date:2023-11-27
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Structural basis of connexin-36 gap junction channel inhibition.
Cell Discov, 10, 2024
8R7P
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BU of 8r7p by Molmil
human connexin-36 gap junction channel
Descriptor: Gap junction delta-2 protein
Authors:Ding, X.Y, Blum, T.B, Korkhov, V.M.
Deposit date:2023-11-27
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Structural basis of connexin-36 gap junction channel inhibition.
Cell Discov, 10, 2024
8QOJ
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BU of 8qoj by Molmil
human connexin-36 gap junction channel in complex with mefloquine
Descriptor: Gap junction delta-2 protein, Mefloquine
Authors:Ding, X.Y, Blum, T.B, Korkhov, V.M.
Deposit date:2023-09-29
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.13 Å)
Cite:Structural basis of connexin-36 gap junction channel inhibition.
Cell Discov, 10, 2024
8QA2
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BU of 8qa2 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA1
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BU of 8qa1 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG - Hemichannel classification NFlex conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8Q9Z
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BU of 8q9z by Molmil
Cryo-EM structure of Cx26 gap junction K125E mutant in bicarbonate buffer (classification on hemichannel)
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA3
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BU of 8qa3 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; NFlex conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA0
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BU of 8qa0 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG - hemichannel classification - NConst conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8IYG
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BU of 8iyg by Molmil
Human neuronal gap junction channel connexin 36
Descriptor: CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, Gap junction delta-2 protein
Authors:Mao, W.X, Chen, S.S.
Deposit date:2023-04-04
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Assembly mechanisms of the neuronal gap junction channel connexin 36 elucidated by Cryo-EM.
Arch.Biochem.Biophys., 754, 2024
8GN8
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BU of 8gn8 by Molmil
structure of human connexin 40.1 pentameric hemichannel by cryoEM
Descriptor: Gap junction delta-4 protein
Authors:Zhang, H, Wang, D.P.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:structure of human connexin 40.1 intercellular gap junction channel by cryoEM
To Be Published
8GN7
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BU of 8gn7 by Molmil
structure of human connexin 40.1 intercellular gap junction channel by cryoEM
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, Gap junction delta-4 protein, ...
Authors:Zhang, H, Wang, D.P.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:structure of human connexin 40.1 intercellular gap junction channel by cryoEM
To Be Published
8GNB
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BU of 8gnb by Molmil
structure of human connexin 40.1 side-by-side decamer channel by cryoEM
Descriptor: Gap junction delta-4 protein
Authors:Zhang, H, Wang, D.P.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:structure of human connexin 40.1 side-by-side decamer channel by cryoEM
To Be Published
7XL8
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BU of 7xl8 by Molmil
Human Cx36/GJD2 (N-terminal deletion mutant) gap junction channel in soybean lipids (D6 symmetry)
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-04-21
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7ZXN
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BU of 7zxn by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: CHOLESTEROL, Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXO
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BU of 7zxo by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXQ
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BU of 7zxq by Molmil
cryo-EM structure of Connexin 32 R22G mutation hemi channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXP
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BU of 7zxp by Molmil
cryo-EM structure of Connexin 32 R22G mutation gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXM
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BU of 7zxm by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.14 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXT
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BU of 7zxt by Molmil
cryo-EM structure of Connexin 32 W3S mutation hemi channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7XKK
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BU of 7xkk by Molmil
Human Cx36/GJD2 gap junction channel in detergents
Descriptor: Gap junction delta-2 protein
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-04-19
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
8HKP
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BU of 8hkp by Molmil
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C6 symmetry)
Descriptor: Gap junction delta-2 protein, Lauryl Maltose Neopentyl Glycol
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-11-27
Release date:2023-03-22
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XNH
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BU of 7xnh by Molmil
Human Cx36/GJD2 gap junction channel with pore-lining N-terminal helices in soybean lipids
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-04-28
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XKI
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BU of 7xki by Molmil
Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry)
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein,Soluble cytochrome b562
Authors:Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H.
Deposit date:2022-04-19
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XNV
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BU of 7xnv by Molmil
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C6 symmetry)
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-04-29
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XKT
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BU of 7xkt by Molmil
Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHOLESTEROL HEMISUCCINATE, ...
Authors:Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H.
Deposit date:2022-04-20
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023

 

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PDB entries from 2024-09-18

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