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4RD4
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BU of 4rd4 by Molmil
Structure of aIF2 gamma from sulfolobus solfataricus bound to gdpnp
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
2C78
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BU of 2c78 by Molmil
EF-Tu complexed with a GTP analog and the antibiotic pulvomycin
Descriptor: (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOX ACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL 6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE, ELONGATION FACTOR TU-A, MAGNESIUM ION, ...
Authors:Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P.
Deposit date:2005-11-18
Release date:2006-03-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
6U43
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BU of 6u43 by Molmil
Crystal structure of Methanoperedens nitroreducens elongation factor 2 H595N bound to GMPPCP and magnesium (triclinic crystal form)
Descriptor: CHLORIDE ION, Elongation factor 2, MAGNESIUM ION, ...
Authors:Fenwick, M.K, Ealick, S.E.
Deposit date:2019-08-22
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of elongation factor 2 switching
Curr Res Struct Biol, 2, 2020
4RCZ
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BU of 4rcz by Molmil
Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDPNP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.429 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
4RD1
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BU of 4rd1 by Molmil
Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GTP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
4TMX
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BU of 4tmx by Molmil
Translation initiation factor eIF5B (517-858) mutant D533N from C. thermophilum, bound to GTP and sodium
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Kuhle, B, Ficner, R.
Deposit date:2014-06-02
Release date:2014-09-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4TMV
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BU of 4tmv by Molmil
Translation initiation factor eIF5B (517-858) from C. thermophilum, bound to GTPgammaS and Sodium
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Kuhle, B, Ficner, R.
Deposit date:2014-06-02
Release date:2014-09-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4TMW
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BU of 4tmw by Molmil
Translation initiation factor eIF5B (517-858) from C. thermophilum, bound to GTP and Sodium
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ...
Authors:Kuhle, B, Ficner, R.
Deposit date:2014-06-02
Release date:2014-09-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4TMT
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BU of 4tmt by Molmil
Translation initiation factor eIF5B (517-858) mutant D533A from C. thermophilum, bound to GTPgammaS
Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ...
Authors:Kuhle, B, Ficner, R.
Deposit date:2014-06-02
Release date:2014-09-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4RD2
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BU of 4rd2 by Molmil
Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GDPNP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.585 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
5H7K
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BU of 5h7k by Molmil
Crystal structure of Elongation factor 2 GDP-form
Descriptor: Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE
Authors:Tanzawa, T, Kato, K, Uchiumi, T, Yao, M.
Deposit date:2016-11-18
Release date:2018-02-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
5TV2
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BU of 5tv2 by Molmil
Crystal structure of a fragment (1-405) of an elongation factor G from Vibrio vulnificus CMCP6
Descriptor: Elongation factor G
Authors:Filippova, E.V, Minasov, G, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-11-07
Release date:2016-11-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a fragment (1-405) of an elongation factor G from Vibrio vulnificus CMCP6
To Be Published
2C77
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BU of 2c77 by Molmil
EF-Tu complexed with a GTP analog and the antibiotic GE2270 A
Descriptor: DI(HYDROXYETHYL)ETHER, ELONGATION FACTOR TU-B, MAGNESIUM ION, ...
Authors:Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P.
Deposit date:2005-11-18
Release date:2006-03-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
2DY1
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BU of 2dy1 by Molmil
Crystal structure of EF-G-2 from Thermus thermophilus
Descriptor: Elongation factor G, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Wang, H, Takemoto, C, Murayama, K, Terada, T, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-09-04
Release date:2007-09-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of EF-G-2 from Thermus thermophilus
To be Published
4RJL
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BU of 4rjl by Molmil
Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus complexed with GDPCP
Descriptor: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, FORMIC ACID, MAGNESIUM ION, ...
Authors:Kravchenko, O.V, Nikonov, O.S, Arhipova, V.I, Stolboushkina, E.A, Gabdulkhakov, A.G, Nikulin, A.D, Garber, M.B, Nikonov, S.V.
Deposit date:2014-10-09
Release date:2015-11-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6401 Å)
Cite:Crystal structure of gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with GDPCP at 1.64A resolution
To be Published
4RCY
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BU of 4rcy by Molmil
Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GTP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
5O8W
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BU of 5o8w by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor: Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ...
Authors:Wirth, C, Andersen, G.R, Hunte, C.
Deposit date:2017-06-14
Release date:2017-08-23
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
1F60
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BU of 1f60 by Molmil
CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor: ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA
Authors:Andersen, G.R, Pedersen, L, Valente, L, Kinzy, T.G, Nyborg, J.
Deposit date:2000-06-19
Release date:2000-07-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
4RD3
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BU of 4rd3 by Molmil
Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GDP and Pi
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
7YZN
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BU of 7yzn by Molmil
Structure of C-terminally truncated aIF5B from Pyrococcus abyssi complexed with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable translation initiation factor IF-2, ...
Authors:Bourgeois, G, Schmitt, E, Mechulam, Y, Coureux, P.D, Kazan, R.
Deposit date:2022-02-21
Release date:2022-06-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Role of aIF5B in archaeal translation initiation.
Nucleic Acids Res., 50, 2022
1EXM
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BU of 1exm by Molmil
CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP.
Descriptor: ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Hogg, T, Mesters, J.R, Hilgenfeld, R.
Deposit date:2000-05-03
Release date:2000-06-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Insights into the GTPase Mechanism of EF-Tu from Structural Studies
The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions, 28, 2000
4RD0
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BU of 4rd0 by Molmil
Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDP
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.713 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
4LBW
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BU of 4lbw by Molmil
Identifying ligand binding hot spots in proteins using brominated fragments
Descriptor: AMMONIUM ION, Elongation factor Tu-A, MAGNESIUM ION, ...
Authors:Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P.
Deposit date:2013-06-21
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.741 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
6B8D
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BU of 6b8d by Molmil
1.78 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-405) of Elongation Factor G from Haemophilus influenzae
Descriptor: CHLORIDE ION, Elongation factor G
Authors:Minasov, G, Shuvalova, L, Dubrovska, I, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-10-06
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:1.78 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-405) of Elongation Factor G from Haemophilus influenzae.
To Be Published
1KK1
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BU of 1kk1 by Molmil
Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDPNP-Mg2+
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ZINC ION, ...
Authors:Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2001-12-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002

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