PDB: 250 件ウェブページステータス検索Chemie searchBIRD

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3QL9	Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide 分子名称: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3 著者 Xiang, B, Li, H. 登録日 2011-02-02 公開日 2011-06-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (0.93 Å) 主引用文献 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome Nat.Struct.Mol.Biol., 18, 2011
2V89	Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide at 1.1A resolution 分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION 著者 Ramon-Maiques, S, Yang, W. 登録日 2007-08-03 公開日 2007-12-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Rag2 Phd Finger Couples Histone H3 Lysine 4 Trimethylation with V(D)J Recombination. Nature, 450, 2007
6LUJ	Crystal structure of the SAMD1 SAM domain 分子名称: Atherin, SULFATE ION 著者 Cao, Y, Zhou, Y, Wang, Z. 登録日 2020-01-29 公開日 2021-02-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. Sci Adv, 7, 2021
7M10	PHF2 PHD Domain Complexed with Peptide From N-terminus of VRK1 分子名称: FORMIC ACID, Lysine-specific demethylase PHF2, Serine/threonine-protein kinase VRK1 N-terminus peptide, ... 著者 Horton, J.R, Cheng, X. 登録日 2021-03-11 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions. Biochem.J., 478, 2021
7ZMX	Crystal structure of the Plant Homeodomain (PHD) of human ING3 分子名称: CALCIUM ION, Inhibitor of growth protein 3, ZINC ION 著者 Ferreras, M.O, Medrano, F.J, Blanco, F.J. 登録日 2022-04-20 公開日 2023-05-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural analysis of ING3 protein and histone H3 binding. Int.J.Biol.Macromol., 242, 2023
3MEA	Crystal structure of the SGF29 in complex with H3K4me3 分子名称: Histone H3, SAGA-associated factor 29 homolog 著者 Bian, C, Xu, C, Tempel, W, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-03-31 公開日 2010-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. Embo J., 30, 2011
7BED	X-ray structure of WDR5 bound to the WDR5 win motif peptide 分子名称: SULFATE ION, WD repeat-containing protein 5 著者 McVey, C.E, Kaye, K.M. 登録日 2020-12-23 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49, 2021
3MEU	Crystal structure of SGF29 in complex with H3R2me2sK4me3 分子名称: Histone H3, SAGA-associated factor 29 homolog, SULFATE ION 著者 Bian, C.B, Xu, C, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-03-31 公開日 2010-04-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. Embo J., 30, 2011
5WXH	Crystal structure of TAF3 PHD finger bound to H3K4me3 分子名称: Histone H3K4me3, Transcription initiation factor TFIID subunit 3, ZINC ION 著者 Zhao, S, Huang, J, Li, H. 登録日 2017-01-07 公開日 2017-08-16 最終更新日 2017-09-13 実験手法 X-RAY DIFFRACTION (1.297 Å) 主引用文献 Kinetic and high-throughput profiling of epigenetic interactions by 3D-carbene chip-based surface plasmon resonance imaging technology Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4L7X	Crystal structure of the DIDO PHD finger in complex with H3K4me3 分子名称: Death-inducer obliterator 1, Histone H3 peptide, ZINC ION 著者 Tong, Q, Gatchalian, J, Kutateladze, T.G. 登録日 2013-06-14 公開日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Dido3 PHD Modulates Cell Differentiation and Division. Cell Rep, 4, 2013
3ME9	Crystal structure of SGF29 in complex with H3K4me3 peptide 分子名称: GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ... 著者 Bian, C, Tempel, W, Xu, C, Guo, Y, Dong, A, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-03-31 公開日 2010-04-28 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. Embo J., 30, 2011
5XVJ	Crystal structure of AL7 PAL domain 分子名称: PHD finger protein ALFIN-LIKE 7, SULFATE ION 著者 Peng, L, Wang, L.L, Huang, Y. 登録日 2017-06-28 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5WLF	Crystal structure of the apo PPS PHD finger 分子名称: GLYCEROL, Protein partner of snf, isoform A, ... 著者 Klein, B.J, Kutateladze, T.G. 登録日 2017-07-26 公開日 2017-10-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO. Structure, 25, 2017
5F5A	Crystal Structure of human JMJD2D complexed with KDOAM16 分子名称: 1,2-ETHANEDIOL, 2-[(furan-2-ylmethylamino)methyl]pyridine-4-carboxylic acid, Lysine-specific demethylase 4D, ... 著者 Krojer, T, Vollmar, M, Crawley, L, Bradley, A.R, Szykowska, A, Ruda, G.F, Yang, H, Burgess-Brown, N, Brennan, P, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U, von Delft, F, Structural Genomics Consortium (SGC) 登録日 2015-12-04 公開日 2015-12-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
7OCB	Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine, CHLORIDE ION, ... 著者 Johansson, C, Krojer, T, Park, K, Xiong, Y, Jin, J, Oppermann, U. 登録日 2021-04-26 公開日 2022-05-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B To Be Published
2PUY	Crystal Structure of the BHC80 PHD finger 分子名称: Histone H3, PHD finger protein 21A, ZINC ION 著者 Horton, J.R, Cheng, X, Collins, R.E. 登録日 2007-05-09 公開日 2007-08-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature, 448, 2007
4L58	Crystal structure of the MLL5 PHD finger in complex with H3K4me3 分子名称: Histone H3 peptide, Histone-lysine N-methyltransferase MLL5, ZINC ION 著者 Tong, Q, Ali, M, Kutateladze, T.G. 登録日 2013-06-10 公開日 2013-06-26 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Molecular basis for chromatin binding and regulation of MLL5. Proc.Natl.Acad.Sci.USA, 110, 2013
3MP6	Complex Structure of Sgf29 and dimethylated H3K4 分子名称: H3K4me2 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Li, J, Wu, M, Ruan, J, Zang, J. 登録日 2010-04-25 公開日 2011-05-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation Embo J., 30, 2011
3QZT	Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form II 分子名称: GLYCEROL, Histone H4, Nucleosome-remodeling factor subunit BPTF 著者 Li, H, Ruthenburg, A.J, Patel, D.J. 登録日 2011-03-07 公開日 2011-06-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions. Cell(Cambridge,Mass.), 145, 2011
4QL1	Crystal structure of human WDR5 in complex with compound OICR-9429 分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, ... 著者 Dong, A, Dombrovski, L, Walker, J.R, Getlik, M, Kuznetsova, E, Smil, D, Barsyte, D, Li, F, Poda, G, Senisterra, G, Marcellus, R, Al-Awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) 登録日 2014-06-10 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia. Nat.Chem.Biol., 11, 2015
7BCY	X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide 分子名称: ORF 73, WD repeat-containing protein 5 著者 McVey, C.E, Kaye, K.M. 登録日 2020-12-21 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49, 2021
6LQF	Crystal structure of Arabidopsis ARID5 ARID-PHD cassette in complex with H3K4me3 peptide and DNA 分子名称: 15-mer peptide from Histone H3.2, AT-rich interactive domain-containing protein 4, DNA (5'-D(*TP*TP*TP*AP*GP*AP*TP*CP*TP*AP*AP*A)-3'), ... 著者 Liu, R, Du, J. 登録日 2020-01-13 公開日 2020-06-03 最終更新日 2020-08-19 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Dual Recognition of H3K4me3 and DNA by the ISWI Component ARID5 Regulates the Floral Transition in Arabidopsis. Plant Cell, 32, 2020
6I8Y	Crystal structure of Spindlin1 in complex with the Methyltransferase inhibitor A366 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 5'-methoxy-6'-[3-(pyrrolidin-1-yl)propoxy]spiro[cyclobutane-1,3'-indol]-2'-amine, ... 著者 Srikannathasan, V, Johansson, C, Gileadi, C, Shrestha, L, Sorrell, F.J, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. 登録日 2018-11-21 公開日 2018-12-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. J.Med.Chem., 62, 2019
5SVX	MORC3 CW in complex with histone H3K4me3 分子名称: H3K4me3, MORC family CW-type zinc finger protein 3, ZINC ION 著者 Tong, Q, Andrews, F.H, Kutateladze, T.G. 登録日 2016-08-08 公開日 2016-10-05 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase. Cell Rep, 16, 2016
6I8L	Crystal structure of Spindlin1 in complex with the inhibitor TD001851a 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-(cyclopropylmethoxy)-6'-[3-(1,3-dihydroisoindol-2-yl)propoxy]spiro[cyclopentane-1,3'-indole]-2'-amine, ... 著者 Johansson, C, Fagan, V, Brennan, P.E, Sorrell, F.J, Krojer, T, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. 登録日 2018-11-20 公開日 2018-12-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. J.Med.Chem., 62, 2019

 

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