7OCB

Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B

Summary for 7OCB

• Entry DOI: 10.2210/pdb7ocb/pdb
• Descriptor: Spindlin-1, 7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine, PHOSPHATE ION, ... (8 entities in total)
• Functional Keywords: chromatin, epigenetics, methyl reader, inhibitor, cell cycle
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 26549.36

Authors

Johansson, C.,Krojer, T.,Park, K.,Xiong, Y.,Jin, J.,Oppermann, U. (deposition date: 2021-04-26, release date: 2022-05-04, Last modification date: 2024-01-31)

• Primary citation: Johansson, C.,Krojer, T.,Park, K.,Xiong, Y.,Jin, J.,Oppermann, U.; Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.42 Å)